An antioxidant lignan and other constituents from the root bark of Hibiscus syriacus

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Title
An antioxidant lignan and other constituents from the root bark of Hibiscus syriacus
Author(s)
Sang Jun Lee; Young Sook Yun; In Kyoung Lee; In Ja Ryoo; Bong Sik Yun; Ick Dong Yoo
Bibliographic Citation
Planta Medica, vol. 65, pp. 658-660
Publication Year
1999
Abstract
A new lignan named as hibiscuside, (+)-pinoresinol 4-O-[β- glucopyranosyl (1→2)-α-rhamnoside] (1), and a known lignan, syringaresinol (2) were isolated from the root bark of Hibiscus syriacus together with two feruloyltyramines (3,4) and three known isoflavonoids (5, 6,7). The structures of these compounds have been established on the basis of their NMR, mass, UV spectra. Among these phenolic compounds, 6-O-acetyldaidzin (5), 6-O-acetylgenistin (6), and 3'-hydroxydaidzein (7) with IC50 values of 8.2, 10.6, and 4.1 μM, respectively, significantly inhibited lipid peroxidation in rat liver microsomes. Hibiscuside (1), E- and Z-N-feruloyl tyramines (3,4) exhibited moderate antioxidant activity.
ISSN
0032-0943
Publisher
Georg Thieme Verlag Kg
DOI
http://dx.doi.org/10.1055/s-2006-960841
Type
Article
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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