A Novel HLA-DR12 Allele (DRB1*1206) Found in a Korean B-Cell Line

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Title
A Novel HLA-DR12 Allele (DRB1*1206) Found in a Korean B-Cell Line
Author(s)
C Y Maeng; K H Kim; J H Kang; H Han; Kil Lyong Kim
Bibliographic Citation
Tissue Antigens, vol. 53, pp. 516-518
Publication Year
1999
Abstract
At least 6 HLA-DRB1*12 alleles have been identified to date with nucleotide polymorphism occurring at codons 37, 57-58, 60, 67, 85 and 87. In this report, we describe the identification of another new HLA-DRB1*12 allele: DRB1*1206. This novel allele was found in an Epstein-Barr virus (EBV)-transformed Korean B-cell line 'K-KT' having the HLA-phenotype A3, 24; B44, 61; Cw3; Bw4, 6; DR12, 13 during full-length cDNA isolation for cell line characterization and for production of HLA-DR recombinant proteins. The allele was identified initially by cycle sequencing of subcloned HLA-DRB full-length cDNA.
Keyword
Asymmetric PCR-SSCPcDNA cloningHLA-DRB1*1206Korean B-cell line
ISSN
0001-2815
Publisher
Wiley
DOI
http://dx.doi.org/10.1034/j.1399-0039.1999.530510.x
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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