Inhibitory constituents against HIV-1 protease from Agastache rugosa

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Title
Inhibitory constituents against HIV-1 protease from Agastache rugosa
Author(s)
Byung Sun Min; Masao Hattori; Hyeong Kyu Lee; Young Ho Kim
Bibliographic Citation
Archives of Pharmacal Research, vol. 22, no. 1, pp. 75-77
Publication Year
1999
Abstract
Two diterpenoid compounds, agastanol (1) and agastaquinone (2), were isolated from the roots of Agastache rugosa (Labiatae). Compound 1 and 2 showed significant inhibitory effects against human immunodeficiency virus type 1 (HIV-1) protease activity with IC50 values of 360 and 87 μm, respectively.
Keyword
Agastache rugosaLabiataeAgastanolAgastaquinoneAnti-HIV-1 protease activity
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/BF02976440
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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