Antioxidant compounds from the root bark of Hibiscus syriacus

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Antioxidant compounds from the root bark of Hibiscus syriacus
Sang Jun Lee; Young Sook Yun; In Kyoung Lee; In Ja Ryoo; Bong Sik Yun; Ick Dong Yoo
Bibliographic Citation
Korean Journal of Plant Resources, vol. 12, no. 2, pp. 110-117
Publication Year
A new lignan named as hibiscuside, (+) pinoresinol 4-O-[-glucopyranosyl (12) -rhamnoside] (1), and a known lignan, syringaresinol (2) were isolated from the root bark of Hibiscus syriacus together with two feruloyltyramines (3,4) and three known isoflavonoids (5,6,7). The structures of these compounds have been established on the basis of their NMR, Mass, UV spectra. Among these phenolic compounds, 6-O-acetyl daidzin (5), 6-O-acetyl genistin (6), and 3-hydroxy daidzein (7) with IC50 values of 8.2, 10.6, and 4.1 M, respectively, significantly inhibited lipid peroxidation in rat liver microsomes. Hibiscuside (1), E and Z-N-feruloyl tyramines (3,4) exhibited moderate antioxidant activity.
Korea Soc-Assoc-Inst
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Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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