Immunomodulating activity of a polysaccharide isolated from mori cortex radicis

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dc.contributor.authorHwan Mook Kim-
dc.contributor.authorSang Bae Han-
dc.contributor.authorKi Hoon Lee-
dc.contributor.authorChang Woo Lee-
dc.contributor.authorChul Young Kim-
dc.contributor.authorEun Ju Lee-
dc.contributor.authorHoon Huh-
dc.date.accessioned2017-04-19T08:57:03Z-
dc.date.available2017-04-19T08:57:03Z-
dc.date.issued2000-
dc.identifier.issn02536269-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/5085-
dc.description.abstractThe immunomodulating activity of a polysaccharide isolated from Morus alba (PMA) root bark was examined in murine splenic lymphocytes. PMA enhanced proliferation of splenic lymphocytes in a synergistic manner in the presence of mitogens. However, PMA suppressed primary IgM antibody production from B cells, which was activated with lipopolysaccharide, a polyclonal activator, or immunized with a T-cell dependent antigen sheep red blood cells. Our observations showed that the immunomodulating activity of PMA increased lymphocyte proliferation and that PMA decreased antibody production from B cells, which was distinct from those of other plant-originated polysaccharides.-
dc.publisherPharmaceutical Soc Korea-
dc.titleImmunomodulating activity of a polysaccharide isolated from mori cortex radicis-
dc.title.alternativeImmunomodulating activity of a polysaccharide isolated from mori cortex radicis-
dc.typeArticle-
dc.citation.titleArchives of Pharmacal Research-
dc.citation.number3-
dc.citation.endPage242-
dc.citation.startPage240-
dc.citation.volume23-
dc.contributor.affiliatedAuthorKi Hoon Lee-
dc.contributor.affiliatedAuthorChang Woo Lee-
dc.contributor.alternativeName김환묵-
dc.contributor.alternativeName한상배-
dc.contributor.alternativeName이기훈-
dc.contributor.alternativeName이창우-
dc.contributor.alternativeName김철영-
dc.contributor.alternativeName이은주-
dc.contributor.alternativeName허훈-
dc.identifier.bibliographicCitationArchives of Pharmacal Research, vol. 23, no. 3, pp. 240-242-
dc.identifier.doi10.1007/BF02976452-
dc.subject.keywordimmunomodulation-
dc.subject.keywordMorus alba-
dc.subject.keywordpolysaccharide-
dc.subject.keywordproliferation-
dc.subject.keyworddifferentiation-
dc.subject.keywordantibody production-
dc.subject.localimmunomodulation-
dc.subject.localImmunomodulation-
dc.subject.localMorus alba-
dc.subject.localpolysaccharide-
dc.subject.localPolysaccharide-
dc.subject.localproliferation-
dc.subject.localProliferation-
dc.subject.localdifferentiation-
dc.subject.localDifferentiation-
dc.subject.localantibody production-
dc.subject.localAntibody production-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Division of Bioinfrastructure > Laboratory Animal Resource Center > 1. Journal Articles
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