DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hwan Mook Kim | - |
dc.contributor.author | Sang Bae Han | - |
dc.contributor.author | Ki Hoon Lee | - |
dc.contributor.author | Chang Woo Lee | - |
dc.contributor.author | Chul Young Kim | - |
dc.contributor.author | Eun Ju Lee | - |
dc.contributor.author | Hoon Huh | - |
dc.date.accessioned | 2017-04-19T08:57:03Z | - |
dc.date.available | 2017-04-19T08:57:03Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/5085 | - |
dc.description.abstract | The immunomodulating activity of a polysaccharide isolated from Morus alba (PMA) root bark was examined in murine splenic lymphocytes. PMA enhanced proliferation of splenic lymphocytes in a synergistic manner in the presence of mitogens. However, PMA suppressed primary IgM antibody production from B cells, which was activated with lipopolysaccharide, a polyclonal activator, or immunized with a T-cell dependent antigen sheep red blood cells. Our observations showed that the immunomodulating activity of PMA increased lymphocyte proliferation and that PMA decreased antibody production from B cells, which was distinct from those of other plant-originated polysaccharides. | - |
dc.publisher | Pharmaceutical Soc Korea | - |
dc.title | Immunomodulating activity of a polysaccharide isolated from mori cortex radicis | - |
dc.title.alternative | Immunomodulating activity of a polysaccharide isolated from mori cortex radicis | - |
dc.type | Article | - |
dc.citation.title | Archives of Pharmacal Research | - |
dc.citation.number | 3 | - |
dc.citation.endPage | 242 | - |
dc.citation.startPage | 240 | - |
dc.citation.volume | 23 | - |
dc.contributor.affiliatedAuthor | Hwan Mook Kim | - |
dc.contributor.affiliatedAuthor | Sang Bae Han | - |
dc.contributor.affiliatedAuthor | Ki Hoon Lee | - |
dc.contributor.affiliatedAuthor | Chang Woo Lee | - |
dc.contributor.alternativeName | 김환묵 | - |
dc.contributor.alternativeName | 한상배 | - |
dc.contributor.alternativeName | 이기훈 | - |
dc.contributor.alternativeName | 이창우 | - |
dc.contributor.alternativeName | 김철영 | - |
dc.contributor.alternativeName | 이은주 | - |
dc.contributor.alternativeName | 허훈 | - |
dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 23, no. 3, pp. 240-242 | - |
dc.identifier.doi | 10.1007/BF02976452 | - |
dc.subject.keyword | immunomodulation | - |
dc.subject.keyword | Morus alba | - |
dc.subject.keyword | polysaccharide | - |
dc.subject.keyword | proliferation | - |
dc.subject.keyword | differentiation | - |
dc.subject.keyword | antibody production | - |
dc.subject.local | immunomodulation | - |
dc.subject.local | Immunomodulation | - |
dc.subject.local | Morus alba | - |
dc.subject.local | Polysaccharides | - |
dc.subject.local | polysaccharide | - |
dc.subject.local | Polysaccharide | - |
dc.subject.local | proliferation | - |
dc.subject.local | Proliferation | - |
dc.subject.local | differentiation | - |
dc.subject.local | Differentiation | - |
dc.subject.local | Antibody production | - |
dc.subject.local | antibody production | - |
dc.description.journalClass | Y | - |
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