Flavonol glycoside gallate and ferulate esters from Persicaria lapathifolia as inhibitors of superoxide production in human monocytes stimulated by unopsonized zymosan

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dc.contributor.authorYoung Soo Kim-
dc.contributor.authorDae Sig Jang-
dc.contributor.authorSi Hyung Park-
dc.contributor.authorJi Eun Yun-
dc.contributor.authorBo Kyung Min-
dc.contributor.authorKyung Rak Min-
dc.contributor.authorHyeong Kyu Lee-
dc.date.accessioned2017-04-19T08:57:03Z-
dc.date.available2017-04-19T08:57:03Z-
dc.date.issued2000-
dc.identifier.issn0032-0943-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/5091-
dc.description.abstractAerial parts of Persicaria lapathifolia S.F. Gray (Polygonaceae) exhibited an inhibitory effect on superoxide production in unopsonized zymosan-stimulated human monocytes. Two known compounds, quercetin 3-O-β- (2''-galloyl)-glucopyranoside and quercetin 3-O-β-(2''-galloyl)- rhamnopyranoside, and a new compound, quercetin 3-O-β-(6''-feruloyl)- galactopyranoside, were isolated as the inhibitors of superoxide production by activity-guided fractionation. IC50 values were shown at the concentrations of 2.1 μM by quercetin 3-O-β-(2''-galloyl)-glucopyranoside, 1.9 μM by quercetin 3-O-β-(2''-galloyl)-rhamnoypranoside, and 3.5 μM by quercetin 3-O-β-(6''-feruloyl)-galactopyranoside whose inhibitory potencies were similar to oxyphenylbutazone (IC50 = 1.9 μM) as a positive control.-
dc.publisherGeorg Thieme Verlag Kg-
dc.titleFlavonol glycoside gallate and ferulate esters from Persicaria lapathifolia as inhibitors of superoxide production in human monocytes stimulated by unopsonized zymosan-
dc.title.alternativeFlavonol glycoside gallate and ferulate esters from Persicaria lapathifolia as inhibitors of superoxide production in human monocytes stimulated by unopsonized zymosan-
dc.typeArticle-
dc.citation.titlePlanta Medica-
dc.citation.number1-
dc.citation.endPage74-
dc.citation.startPage72-
dc.citation.volume66-
dc.contributor.affiliatedAuthorJi Eun Yun-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.alternativeName김영수-
dc.contributor.alternativeName장대식-
dc.contributor.alternativeName박시형-
dc.contributor.alternativeName윤지은-
dc.contributor.alternativeName민보경-
dc.contributor.alternativeName민경락-
dc.contributor.alternativeName이형규-
dc.identifier.bibliographicCitationPlanta Medica, vol. 66, no. 1, pp. 72-74-
dc.identifier.doi10.1055/s-0029-1243112-
dc.description.journalClassY-
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