Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1
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- Title
- Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1
- Author(s)
- Ha Won Jeong; Mi Ran Kim; Kwang Hee Son; Mi Young Han; Ji Hong Ha; Matthieu Garnier; Laurent Meijer; Byoung-Mog Kwon
- Bibliographic Citation
- Bioorganic & Medicinal Chemistry Letters, vol. 10, no. 16, pp. 1819-1822
- Publication Year
- 2000
- Abstract
- A series of cinnamaldehydes was synthesized for the study of inhibitory activity against cyclin dependent kinases (CDKs). A couple of compounds selectively inhibited cyclin D1-CDK4 with an IC50 value of 7-18 μM.
- ISSN
- 0960-894X
- Publisher
- Elsevier
- Full Text Link
- http://dx.doi.org/10.1016/S0960-894X(00)00357-7
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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