Cyclo(Dehydroala-l-Leu), an α-glucosidase inhibitor from Penicillium sp. F70614

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dc.contributor.authorOh Sung Kwon-
dc.contributor.authorSang Ho Park-
dc.contributor.authorBong Sik Yun-
dc.contributor.authorYu Ryang Pyun-
dc.contributor.authorChang Jin Kim-
dc.date.accessioned2017-04-19T08:57:10Z-
dc.date.available2017-04-19T08:57:10Z-
dc.date.issued2000-
dc.identifier.issn0021-8820-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/5137-
dc.description.abstractA diketopiperazine (1) has been isolated from the culture broth of Penicillium sp. F70614 and its structure has been determined to be cyclo(dehydroala-L-Leu) by various spectroscopic analyses. This compound selectively inhibited yeast α-glucosidase and porcine intestinal α-glucosidase with IC50 values of 35 and 50 μg/ml, respectively. However, it did not show significant inhibitory effects against almond β-glucosidase, Aspergillus α-galactosidase, Escherichia coli β-galactosidase and jack bean α-mannosidase.-
dc.publisherSpringer-Nature Pub Group-
dc.titleCyclo(Dehydroala-l-Leu), an α-glucosidase inhibitor from Penicillium sp. F70614-
dc.title.alternativeCyclo(Dehydroala-l-Leu), an α-glucosidase inhibitor from Penicillium sp. F70614-
dc.typeArticle-
dc.citation.titleJournal of Antibiotics-
dc.citation.number9-
dc.citation.endPage958-
dc.citation.startPage954-
dc.citation.volume53-
dc.contributor.affiliatedAuthorOh Sung Kwon-
dc.contributor.affiliatedAuthorBong Sik Yun-
dc.contributor.affiliatedAuthorChang Jin Kim-
dc.contributor.alternativeName권오성-
dc.contributor.alternativeName박상호-
dc.contributor.alternativeName윤봉식-
dc.contributor.alternativeName변유량-
dc.contributor.alternativeName김창진-
dc.identifier.bibliographicCitationJournal of Antibiotics, vol. 53, no. 9, pp. 954-958-
dc.identifier.doi10.7164/antibiotics.53.954-
dc.description.journalClassY-
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