Three naphthalenes from root bark of Hibiscus syriacus

Cited 28 time in scopus
Metadata Downloads
Title
Three naphthalenes from root bark of Hibiscus syriacus
Author(s)
Ick Dong Yoo; Bong Sik Yun; In Kyung Lee; In Ja Ryoo; Dong Ho Choung; Kyou Hoon Han
Bibliographic Citation
Phytochemistry, vol. 47, no. 5, pp. 799-802
Publication Year
1998
Abstract
Three new naphthalenes, designated as syriacusins A-C, were isolated from the root bark of Hibiscus syriacus. These compounds were identified as 2,7-dihydroxy-6-methyl-8-methoxy-l-naphthalenecarbaldehyde, 2-hydroxy-6- hydroxymethyl-7,8-dimethoxy-l-naphthalenecarbaldehyde, 1-carboxy-2,8- dihydroxy-6-methyl-7-methoxynaphthalenecarbolactone (1 → 8), respectively, on the basis of various spectral studies. The compounds inhibited lipid peroxidation with IC50s of 0.54,5.90 and 1.02 μg ml-1, respectively. The first compound also showed cytotoxicity against some human cancer cell lines with an ED50 of 1.5-2.4 μg ml-1.
Keyword
CytotoxicityHibiscus syriacusLipid peroxidation inhibitory activityMaivaceaeNaph- thalenecarbaldehydeNaphthaleneNaphthalenecarbolactoneRoot barkSyriacusins
ISSN
0031-9422
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/S0031-9422(97)00674-2
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.