Steroidal saponins from the rhizomes of asparagus oligoclonos and their antibacterial activity = 방울비짜루(Asparagus oligoclonos)로부터 분리한 스테로이드 사포닌의 항균활성
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Title
Steroidal saponins from the rhizomes of asparagus oligoclonos and their antibacterial activity = 방울비짜루(Asparagus oligoclonos)로부터 분리한 스테로이드 사포닌의 항균활성
Author(s)
Geum Soog Kim; Jae Duck Seong; Seung Yong Park; Sei Ryang Oh; Yong Ho Kwack
Bibliographic Citation
Journal of Korean Society of Agricul Chem Biot, vol. 43, no. 2, pp. 136-140
Publication Year
2000
Abstract
Two steroidal saponins were isolated from MeOH extract of the rhizomes of Asparagus oligoclonos. Using the spectroscopic techniques of ¹H, ^(13)C NMR and 2D NMR, they were identified as 3-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-(25S) -spirostan-3β-ol and 3-O-[β-D-glucopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranosyl]-(25S)-spirostan-3β-ol, respectively. They were first isolated from A. oligoclonos. The in vitro antibacterial activities as well as antibacterial spectrums against 20 bacteria strains were investigated with MIC test. Both saponins inhibited the growth of 10 bacteria strains at the concentration of 100㎍/㎖.