Effects of medium components on L-ornithine production by Brevibacterium ketoglutamicum

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Title
Effects of medium components on L-ornithine production by Brevibacterium ketoglutamicum
Author(s)
Tae Ho Lee; Yong Keun Chang; Wook Sang Ryu; Bong Hyun Chung; Young Hoon Park
Bibliographic Citation
Biotechnology and Bioprocess Engineering, vol. 1, no. 1, pp. 41-45
Publication Year
1996
Abstract
Effects of yeast extract and ammonium sulfate were investigated on the production of L-ornithine by an arginine auxotroph, Brevibacterium ketoglutamicum in flask and batch cultures. Yeast extract as an arginine source and ammonium sulfate as an inorganic nitrogen source had significant effects on L-ornithine production and cell growth. L-ornithine production was repressed by the excessive addition of arginine Reversion of auxotrophic cells to the wild type was observed when the initial yeast extract concentration was too low. There existed optimum concentrations of yeast extract and ammonium sulfate for L-ornithine production. The effects of yeast extract and ammonium sulfate concentrations on the Leudeking-Piret model parameters were examined to analyze the relationship between cell growth and L-ornithine production.
Keyword
L-ornithineauxotrophbrevibacterium ketoglutamicumL-arginine
ISSN
1226-8372
Publisher
Springer
DOI
http://dx.doi.org/10.1007/BF02949143
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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