A Tetrodotoxin-Producing Vibrio Strain, LM-1, from the Puffer Fish Fugu vermicularis radiatus

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Title
A Tetrodotoxin-Producing Vibrio Strain, LM-1, from the Puffer Fish Fugu vermicularis radiatus
Author(s)
Myoung Ja Lee; Dong Youn Jeong; Woo Seong Kim; Hyun Dae Kim; Cheorl Ho Kim; Won Whan Park; Yong Ha Park; Kyung Sam Kim; Hyung Min Kim; Dong Soo Kim
Bibliographic Citation
Applied and Environmental Microbiology, vol. 66, no. 4, pp. 1698-1701
Publication Year
2000
Abstract
Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.
ISSN
0099-2240
Publisher
Amer Soc Microb
DOI
http://dx.doi.org/10.1128/aem.66.4.1698-1701.2000
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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