Inhibition of telomerase activity by fungus metabolites, CRM646-A and thielavin B

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dc.contributor.authorK Togashi-
dc.contributor.authorH R Ko-
dc.contributor.authorJong Seog Ahn-
dc.contributor.authorH Osada-
dc.date.accessioned2017-04-19T08:58:01Z-
dc.date.available2017-04-19T08:58:01Z-
dc.date.issued2001-
dc.identifier.issn09168451-
dc.identifier.uri10.1271/bbb.65.651ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/5490-
dc.description.abstractWe performed a screening program to identify telomerase inhibitors from our drug source obtained from fungus fermentations, and found that two compounds, CRM646-A and thielavin B, inhibited telomerase activity at doses of 3.2 and 32 μM, respectively. These compounds also inhibited the activity of viral reverse transcriptase at almost the same dose levels which inhibited telomerase activity.-
dc.publisherT&F (Taylor & Francis)-
dc.titleInhibition of telomerase activity by fungus metabolites, CRM646-A and thielavin B-
dc.title.alternativeInhibition of telomerase activity by fungus metabolites, CRM646-A and thielavin B-
dc.typeArticle-
dc.citation.titleBioscience Biotechnology and Biochemistry-
dc.citation.number3-
dc.citation.endPage653-
dc.citation.startPage651-
dc.citation.volume65-
dc.contributor.affiliatedAuthorJong Seog Ahn-
dc.contributor.alternativeNameTogashi-
dc.contributor.alternativeName고학룡-
dc.contributor.alternativeName안종석-
dc.contributor.alternativeNameOsada-
dc.identifier.bibliographicCitationBioscience Biotechnology and Biochemistry, vol. 65, no. 3, pp. 651-653-
dc.identifier.doi10.1271/bbb.65.651-
dc.subject.keywordscreening-
dc.subject.keywordtelomerase-
dc.subject.keywordCRM646-A-
dc.subject.keywordthielavin B-
dc.subject.keywordreverse transcriptase-
dc.subject.localscreening-
dc.subject.localScreening-
dc.subject.localtelomerase-
dc.subject.localTelomerase-
dc.subject.localCRM646-A-
dc.subject.localthielavin B-
dc.subject.localThielavin B-
dc.subject.localreverse transcriptase-
dc.subject.localReverse transcriptase-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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