Physiological constraints in increasing biomass concentration of Escherichia coli B in fed-batch culture

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Title
Physiological constraints in increasing biomass concentration of Escherichia coli B in fed-batch culture
Author(s)
Jae Gu Pan; Joon Shick Rhee; Jean M Lebeault
Bibliographic Citation
Biotechnology Letters, vol. 9, no. 2, pp. 89-94
Publication Year
1987
Abstract
Fed-batch culture ofE.coli B was carried out to obtain high concentration of biomass. After requirement of oxygen was met by sparging the pure oxygen, physiological constraints were delineated. High partial pressure of CO2 caused the decrease of the maximum specific growth rate, whereas fermentative byproducts caused the decrease of biomass yield as well as the maximum specific growth rate.
Keyword
carbon dioxideescherichia colifed batch culturebacterial growth
ISSN
0141-5492
Publisher
Springer
DOI
http://dx.doi.org/10.1007/BF01032744
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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