DC Field | Value | Language |
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dc.contributor.author | Ki Hyeong Rhee | - |
dc.contributor.author | Kyung Hee Choi | - |
dc.contributor.author | Chang Jin Kim | - |
dc.contributor.author | Chang Han Kim | - |
dc.date.accessioned | 2017-04-19T08:58:20Z | - |
dc.date.available | 2017-04-19T08:58:20Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/5557 | - |
dc.description.abstract | The actinomycete strain AMLK-335 was antagonistic to vancomycin-resistant enterococci (VRE). Based on the diaminopimelic acid (DAP) type, and morphological and physiological characteristics revealed by scanning electron microscopy (SEM), AMLK-335 was confirmed to belong to the genus Streptomyces. Analysis of the 16S rDNA nucleotide sequences found AMLK-335 to have a relationship with Streptomyces platensis. The production of antibiotic from this strain was most favorable when cultured on glucose, polypeptone, yeast extract (PY) medium for 6 days at 27 °C. The antibiotic was identified as cyclo(L-phenylalanyl-L-prolyl) by comparing it with the reported MS and NMR spectral data. Cyclo(phe-pro) from the PY cultures of AMLK-335 was most effective against the VRE strains E. faecium (K-98-637) and E. faecalis (K-98-258). Furthermore, cyclo(phe-pro) had antimicrobial activity against Bacillus subtilis, Microcuccs luteus, Staphylococcus aureus, and Saccharomyces cerevisiae, but it was ineffective against Candida albicans, Streptomyces murinus, and Aspergillus niger. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | Identification of Streptomyces sp. AMLK-335 producing antibiotic substance inhibitory to vancomycin-resistant enterococci | - |
dc.title.alternative | Identification of Streptomyces sp. AMLK-335 producing antibiotic substance inhibitory to vancomycin-resistant enterococci | - |
dc.type | Article | - |
dc.citation.title | Journal of Microbiology and Biotechnology | - |
dc.citation.number | 3 | - |
dc.citation.endPage | 474 | - |
dc.citation.startPage | 469 | - |
dc.citation.volume | 11 | - |
dc.contributor.affiliatedAuthor | Chang Jin Kim | - |
dc.contributor.alternativeName | 이기형 | - |
dc.contributor.alternativeName | 최경희 | - |
dc.contributor.alternativeName | 김창진 | - |
dc.contributor.alternativeName | 김창한 | - |
dc.identifier.bibliographicCitation | Journal of Microbiology and Biotechnology, vol. 11, no. 3, pp. 469-474 | - |
dc.subject.keyword | vancomycin-resistant enterococci (VRE) | - |
dc.subject.keyword | 16S rDNA | - |
dc.subject.keyword | streptomyces sp. AMLK-335 | - |
dc.subject.keyword | cyclo (L-phenylalanyl-L-prolyl) | - |
dc.subject.local | vancomycin-resistant enterococci (VRE) | - |
dc.subject.local | 16S rDNA | - |
dc.subject.local | 16s rDNA | - |
dc.subject.local | streptomyces sp. AMLK-335 | - |
dc.subject.local | cyclo (L-phenylalanyl-L-prolyl) | - |
dc.description.journalClass | Y | - |
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