Coumarins with monoamine oxidase Inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus

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Title
Coumarins with monoamine oxidase Inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus
Author(s)
Bong Sik Yun; In Kyoung Lee; In Ja Ryoo; Ick Dong Yoo
Bibliographic Citation
Journal of Natural Products, vol. 64, no. 9, pp. 1238-1240
Publication Year
2001
Abstract
A previously undescribed coumarin and a new coumarino-lignan, together with the known compounds scopoletin and cleomiscosins A, C, and D, have been isolated from the root bark of Hibiscus syriacus, and their structures were assigned on the basis of various spectral studies. The coumarin analogue and scopoletin inhibited monoamine oxidase with moderate IC50 values. The new coumarino-lignan and cleomiscosin C showed lipid peroxidation inhibitory activity comparable to vitamin E.
ISSN
0163-3864
Publisher
Amer Chem Soc
DOI
http://dx.doi.org/10.1021/np0100946
Type
Article
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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