DC Field | Value | Language |
---|---|---|
dc.contributor.author | Maria Palola Giovannoni | - |
dc.contributor.author | Vittorio Dal Piaz | - |
dc.contributor.author | Byoung-Mog Kwon | - |
dc.contributor.author | Mi Kyung Kim | - |
dc.contributor.author | Young Kook Kim | - |
dc.contributor.author | Lucio Toma | - |
dc.contributor.author | Daniela Barlocco | - |
dc.contributor.author | Franco Bernini | - |
dc.contributor.author | Monica Canavesi | - |
dc.date.accessioned | 2017-04-19T08:58:30Z | - |
dc.date.available | 2017-04-19T08:58:30Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 0022-2623 | - |
dc.identifier.uri | 10.1021/jm010807h | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/5627 | - |
dc.description.abstract | Alkyl-5, 6-diphenylpyridazine derivatives combining several main features of ACAT inhibitors, such as a long alkyl side chain linked to a heterocycle and the o-diphenyl system, were synthesized and tested. Moreover, modeling studies on representative terms were performed. Some compounds displayed ACAT inhibition in the micromolar range, both on the enzyme isolated from rat liver microsomes and in cell-free homogenate of murine macrophages. | - |
dc.publisher | Amer Chem Soc | - |
dc.title | 5,6-Diphenylpyridazine derivatives as acyl-CoA : cholesterol acyltransferase inhibitors | - |
dc.title.alternative | 5,6-Diphenylpyridazine derivatives as acyl-CoA : cholesterol acyltransferase inhibitors | - |
dc.type | Article | - |
dc.citation.title | Journal of Medicinal Chemistry | - |
dc.citation.number | 24 | - |
dc.citation.endPage | 4295 | - |
dc.citation.startPage | 4292 | - |
dc.citation.volume | 44 | - |
dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
dc.contributor.affiliatedAuthor | Mi Kyung Kim | - |
dc.contributor.affiliatedAuthor | Young Kook Kim | - |
dc.contributor.alternativeName | Giovannoni | - |
dc.contributor.alternativeName | Piaz | - |
dc.contributor.alternativeName | 권병목 | - |
dc.contributor.alternativeName | 김미경 | - |
dc.contributor.alternativeName | 김영국 | - |
dc.contributor.alternativeName | Toma | - |
dc.contributor.alternativeName | Barlocco | - |
dc.contributor.alternativeName | Bernini | - |
dc.contributor.alternativeName | Canavesi | - |
dc.identifier.bibliographicCitation | Journal of Medicinal Chemistry, vol. 44, no. 24, pp. 4292-4295 | - |
dc.identifier.doi | 10.1021/jm010807h | - |
dc.description.journalClass | Y | - |
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