A New guaianolide as apoptosis inhibitor from Chrysanthemum boreale

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Title
A New guaianolide as apoptosis inhibitor from Chrysanthemum boreale
Author(s)
Jong Rok Lee; Min Suk Yang; Dae Sik Jang; Tae Joung Ha; Ki Min Park; Choong Hwan Lee; Yung Hee Kho; Ki Hun Park
Bibliographic Citation
Planta Medica, vol. 67, no. 6, pp. 585-587
Publication Year
2001
Abstract
The 8-O-acetyl-3,10-dihydroxy-4(15),11(13)-guaiadien-12,6-olide, named borenolide, was isolated from Chrysanthemum boreale M. Borenolide inhibits the etoposide-induced apoptosis in U937 cell with an IC50 value of 6.2 μg/ml. Structural assignment was based on NMR-spectroscopic methods and X-ray crystallographic analysis.
ISSN
0032-0943
Publisher
Georg Thieme Verlag Kg
DOI
http://dx.doi.org/10.1055/s-2001-16477
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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