Negative regulation of filamentous growth and flocculation by Lkh1, a fission yeast LAMMER Kinase homolog

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dc.contributor.authorKun Hoe Kim-
dc.contributor.authorYoung Mi Cho-
dc.contributor.authorWon Hwa Kang-
dc.contributor.authorJi Hoon Kim-
dc.contributor.authorKwan Ho Byun-
dc.contributor.authorYoon Dong Park-
dc.contributor.authorKyung Sook Bae-
dc.contributor.authorHee Moon Park-
dc.date.accessioned2017-04-19T08:58:37Z-
dc.date.available2017-04-19T08:58:37Z-
dc.date.issued2001-
dc.identifier.issn0006-291X-
dc.identifier.uri10.1006/bbrc.2001.6128ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/5672-
dc.description.abstractWe have isolated a full-length cDNA clone that encodes for a Schizosaccharomyces pombe homolog of the dual-specificity protein kinase of the LAMMER family, lkh1 (lammer kinase homolog). The proposed Lkh1 protein contains 575 amino acids. The lkh1+ null mutant is viable, but exhibits flocculation upon reaching stationary phase in liquid media and filamentous adhesion growth on solid media. Analysis of the flocculation activity of the lkh1+ null mutant indicates that asexual aggregation of S. pombe cells into floccules is divalent cation-dependent and galactose-specific. We also demonstrate that the Saccharomyces cerevisiae LAMMER kinase homolog, Kns1, can substitute for the Lkh1 function in S. pombe.-
dc.publisherElsevier-
dc.titleNegative regulation of filamentous growth and flocculation by Lkh1, a fission yeast LAMMER Kinase homolog-
dc.title.alternativeNegative regulation of filamentous growth and flocculation by Lkh1, a fission yeast LAMMER Kinase homolog-
dc.typeArticle-
dc.citation.titleBiochemical and Biophysical Research Communications-
dc.citation.number5-
dc.citation.endPage1242-
dc.citation.startPage1237-
dc.citation.volume289-
dc.contributor.affiliatedAuthorYoon Dong Park-
dc.contributor.affiliatedAuthorKyung Sook Bae-
dc.contributor.alternativeName김근회-
dc.contributor.alternativeName조영미-
dc.contributor.alternativeName강원화-
dc.contributor.alternativeName김지훈-
dc.contributor.alternativeName변관호-
dc.contributor.alternativeName박윤동-
dc.contributor.alternativeName배경숙-
dc.contributor.alternativeName박희문-
dc.identifier.bibliographicCitationBiochemical and Biophysical Research Communications, vol. 289, no. 5, pp. 1237-1242-
dc.identifier.doi10.1006/bbrc.2001.6128-
dc.subject.keywordFilamentous adhesion-
dc.subject.keywordFlocculation-
dc.subject.keywordKns1-
dc.subject.keywordLAMMER kinase-
dc.subject.keywordLkh1-
dc.subject.keywordS. cerevisiae-
dc.subject.keywordS. pombe-
dc.subject.localFilamentous adhesion-
dc.subject.localFlocculation-
dc.subject.localKns1-
dc.subject.localLAMMER kinase-
dc.subject.localLkh1-
dc.subject.localS. cerevisiae-
dc.subject.localS. pombe-
dc.description.journalClassY-
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