A cytotoxic secocycloartenoid from Abies koreana

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dc.contributor.authorHyun Jung Kim-
dc.contributor.authorQuoc Khanh Le-
dc.contributor.authorMi Hyun Lee-
dc.contributor.authorTae Sung Kim-
dc.contributor.authorHyeong Kyu Lee-
dc.contributor.authorYoung Ho Kim-
dc.contributor.authorKi Hwan Bae-
dc.contributor.authorIk Soo Lee-
dc.date.accessioned2017-04-19T08:58:50Z-
dc.date.available2017-04-19T08:58:50Z-
dc.date.issued2001-
dc.identifier.issn0253-6269-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/5747-
dc.description.abstractTwo triterpenoids, 24-methylene-3,4-seco-cycloart-4(28)-en-3-oic acid (1) and 3-oxo-9β- lanosta-7,22Z,24-trien-26,23-olide (6) were isolated from Abies koreana, together with β- sitosterol (2), maltol (3), β-sitosterol-O-β-D-glucoside (4), and hexacosylferulate (5). The structures of the compounds were established based on the spectroscopic data. The cytotoxic activities of triterpenoids have been evaluated using the sulforhodamine B (SRB) method. Compound 1 showed moderate cytotoxicities against human lung carcinoma (A549), ovarian carcinoma (SK-OV-3), malignant melanoma (SK-MEL-2), and colon carcinoma (HCT-15) cell lines.-
dc.publisherPharmaceutical Soc Korea-
dc.titleA cytotoxic secocycloartenoid from Abies koreana-
dc.title.alternativeA cytotoxic secocycloartenoid from Abies koreana-
dc.typeArticle-
dc.citation.titleArchives of Pharmacal Research-
dc.citation.number6-
dc.citation.endPage531-
dc.citation.startPage527-
dc.citation.volume24-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.affiliatedAuthorYoung Ho Kim-
dc.contributor.alternativeName김현정-
dc.contributor.alternativeNameLe-
dc.contributor.alternativeName이미현-
dc.contributor.alternativeName김태성-
dc.contributor.alternativeName이형규-
dc.contributor.alternativeName김영호-
dc.contributor.alternativeName배기환-
dc.contributor.alternativeName이익수-
dc.identifier.bibliographicCitationArchives of Pharmacal Research, vol. 24, no. 6, pp. 527-531-
dc.identifier.doi10.1007/BF02975159-
dc.subject.keyword24-methylene-3,4-seco-cycloart-4(28)-en-3-oic acid-
dc.subject.keyword3- Oxo-9β-lanosta-7,22z,24-trien-26,23-olide-
dc.subject.keywordAbies koreana-
dc.subject.keywordCytotoxicity-
dc.subject.keywordPinaceae-
dc.subject.local24-methylene-3,4-seco-cycloart-4(28)-en-3-oic acid-
dc.subject.local3- Oxo-9β-lanosta-7,22z,24-trien-26,23-olide-
dc.subject.localAbies koreana-
dc.subject.localCytotoxicity-
dc.subject.localcytotoxicity-
dc.subject.localPinaceae-
dc.description.journalClassY-
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