DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hyun Jung Kim | - |
dc.contributor.author | Quoc Khanh Le | - |
dc.contributor.author | Mi Hyun Lee | - |
dc.contributor.author | Tae Sung Kim | - |
dc.contributor.author | Hyeong Kyu Lee | - |
dc.contributor.author | Young Ho Kim | - |
dc.contributor.author | Ki Hwan Bae | - |
dc.contributor.author | Ik Soo Lee | - |
dc.date.accessioned | 2017-04-19T08:58:50Z | - |
dc.date.available | 2017-04-19T08:58:50Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/5747 | - |
dc.description.abstract | Two triterpenoids, 24-methylene-3,4-seco-cycloart-4(28)-en-3-oic acid (1) and 3-oxo-9β- lanosta-7,22Z,24-trien-26,23-olide (6) were isolated from Abies koreana, together with β- sitosterol (2), maltol (3), β-sitosterol-O-β-D-glucoside (4), and hexacosylferulate (5). The structures of the compounds were established based on the spectroscopic data. The cytotoxic activities of triterpenoids have been evaluated using the sulforhodamine B (SRB) method. Compound 1 showed moderate cytotoxicities against human lung carcinoma (A549), ovarian carcinoma (SK-OV-3), malignant melanoma (SK-MEL-2), and colon carcinoma (HCT-15) cell lines. | - |
dc.publisher | Pharmaceutical Soc Korea | - |
dc.title | A cytotoxic secocycloartenoid from Abies koreana | - |
dc.title.alternative | A cytotoxic secocycloartenoid from Abies koreana | - |
dc.type | Article | - |
dc.citation.title | Archives of Pharmacal Research | - |
dc.citation.number | 6 | - |
dc.citation.endPage | 531 | - |
dc.citation.startPage | 527 | - |
dc.citation.volume | 24 | - |
dc.contributor.affiliatedAuthor | Hyeong Kyu Lee | - |
dc.contributor.affiliatedAuthor | Young Ho Kim | - |
dc.contributor.alternativeName | 김현정 | - |
dc.contributor.alternativeName | Le | - |
dc.contributor.alternativeName | 이미현 | - |
dc.contributor.alternativeName | 김태성 | - |
dc.contributor.alternativeName | 이형규 | - |
dc.contributor.alternativeName | 김영호 | - |
dc.contributor.alternativeName | 배기환 | - |
dc.contributor.alternativeName | 이익수 | - |
dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 24, no. 6, pp. 527-531 | - |
dc.identifier.doi | 10.1007/BF02975159 | - |
dc.subject.keyword | 24-methylene-3,4-seco-cycloart-4(28)-en-3-oic acid | - |
dc.subject.keyword | 3- Oxo-9β-lanosta-7,22z,24-trien-26,23-olide | - |
dc.subject.keyword | Abies koreana | - |
dc.subject.keyword | Cytotoxicity | - |
dc.subject.keyword | Pinaceae | - |
dc.subject.local | 24-methylene-3,4-seco-cycloart-4(28)-en-3-oic acid | - |
dc.subject.local | 3- Oxo-9β-lanosta-7,22z,24-trien-26,23-olide | - |
dc.subject.local | Abies koreana | - |
dc.subject.local | Cytotoxicity | - |
dc.subject.local | cytotoxicity | - |
dc.subject.local | Pinaceae | - |
dc.description.journalClass | Y | - |
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