Development of tripeptidyl farnesyltransferase inhibitors

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Title
Development of tripeptidyl farnesyltransferase inhibitors
Author(s)
Hee Yoon Lee; Jeong Hun Sohn; Byoung-Mog Kwon
Bibliographic Citation
Bioorganic & Medicinal Chemistry Letters, vol. 12, no. 12, pp. 1599-1602
Publication Year
2002
Abstract
The first example of tripeptide inhibitors of farnesyltransferase with sub-micromolar inhibition activity was developed based on the fact that CVFM is not a substrate for farnesyltransferase.
ISSN
0960-894X
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/S0960-894X(02)00227-5
Type
Article
Appears in Collections:
Division of Biomedical Research > Genome Editing Research Center > 1. Journal Articles
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