DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choong Hwan Lee | - |
dc.contributor.author | Hyun A Kim | - |
dc.contributor.author | Yung Hee Kho | - |
dc.date.accessioned | 2017-04-19T08:59:01Z | - |
dc.date.available | 2017-04-19T08:59:01Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | 10.1021/np010425e | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/5824 | - |
dc.description.abstract | Investigation of the whole plant of Agastache rugosa resulted in the isolation of two new lignan compounds. Their structures were elucidated as (8S, 7′R, 8′S)-4-hydroxybenzoic acid 4-(4-hydroxy-3-methoxybenzyl)2-(4-hydroxy-3-methoxyphenyl) tetrahydrofuran-3-ylmethyl ester (agastinol, 1) and (7′R, 8′S)-4-hydroxybenzoic acid 4-(hydroxy-3-methoxybenzylidene)-2-(4-hydroxy-3-methoxyphenyl)- tetrahydrofuran-3ylmethyl ester (agastenol, 2). Agastinol and agastenol inhibited etoposide-induced apoptosis in U937 cells with IC50 values of 15.2 and 11.4μg/mL, respectively. | - |
dc.publisher | Amer Chem Soc | - |
dc.title | Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay | - |
dc.title.alternative | Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay | - |
dc.type | Article | - |
dc.citation.title | Journal of Natural Products | - |
dc.citation.number | 3 | - |
dc.citation.endPage | 416 | - |
dc.citation.startPage | 414 | - |
dc.citation.volume | 65 | - |
dc.contributor.affiliatedAuthor | Choong Hwan Lee | - |
dc.contributor.affiliatedAuthor | Hyun A Kim | - |
dc.contributor.affiliatedAuthor | Yung Hee Kho | - |
dc.contributor.alternativeName | 이충환 | - |
dc.contributor.alternativeName | 김현아 | - |
dc.contributor.alternativeName | 고영희 | - |
dc.identifier.bibliographicCitation | Journal of Natural Products, vol. 65, no. 3, pp. 414-416 | - |
dc.identifier.doi | 10.1021/np010425e | - |
dc.description.journalClass | Y | - |
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