Aceriphyllic acid A, a new ACAT inhibitory triterpenoid, from Aceriphyllum rossii
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- Title
- Aceriphyllic acid A, a new ACAT inhibitory triterpenoid, from Aceriphyllum rossii
- Author(s)
- Jae Taek Han; Hae Yeong Kim; Young Doo Park; Youn Hyung Lee; Kang Ro Lee; Byoung-Mog Kwon; Nam In Baek
- Bibliographic Citation
- Planta Medica, vol. 68, no. 6, pp. 558-561
- Publication Year
- 2002
- Abstract
- Two new triterpenoids along with three known ones, 3-oxo-olean-12-en-27-oic acid (1), 3α-hydroxyolean-12-en-27-oic acid (2) and 3β-hydroxyolean-12-en-27-oic acid (3), were isolated from Aceriphyllum rossii. The structures of the new compounds were determined to be a 3α,23-dihydroxyolean-12-en-27-oic acid (4) and a 3α,23-dihydroxyolean-12-en-29-oic acid (5) by spectroscopic and chemical methods; they were designated aceriphyllic acids A and B, respectively. Compounds 2, 3 and 4 remarkably inhibited the activity of ACAT.
- ISSN
- 0032-0943
- Publisher
- Georg Thieme Verlag Kg
- Full Text Link
- http://dx.doi.org/10.1055/s-2002-32565
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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