Inhibitory activity of plant extracts on matrix metalloproteinase-2 = 식물추출물의 matrix metalloproteinase-2에 대한 저해활성

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Title
Inhibitory activity of plant extracts on matrix metalloproteinase-2 = 식물추출물의 matrix metalloproteinase-2에 대한 저해활성
Author(s)
Sang Myung Lee; Hyo Kon Chun; Ho Jae Lee; Choong Hwan Lee; Jin Hee Kim; Yung Hee Kho
Bibliographic Citation
Korean Journal of Pharmacognosy, vol. 33, no. 2, pp. 137-143
Publication Year
2002
Abstract
The inhibitory effects of methanol extracts of 165 medicinal herbs on matrix metalloproteinase-2 (MMP-2) activity were investigated. Amongst the herbal extracts, Youngia denticulate, Platycarya strobilacea, Sedum kamtschaticum, Euscaphis japonica, and Cornus controversa showed a significant inhibitory effect with above 80% at 1 μg/ml. Above mentioned five kind extracts, which exclude polyphenols and/or tannin by techniques for their removal, showed a mild inhibitory effect on MMP-2 activity except for Y. denticulate at the same concentration.
Keyword
matrix metalloproteinase-2youngia denticulate
ISSN
0253-3073
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Division of Bio Technology Innovation > SME Support Center > 1. Journal Articles
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