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- Title
- Inhibitory activity of plant extracts on matrix metalloproteinase-2 = 식물추출물의 matrix metalloproteinase-2에 대한 저해활성
- Author(s)
- Sang Myung Lee; Hyo Kon Chun; Ho Jae Lee; Choong Hwan Lee; Jin Hee Kim; Yung Hee Kho
- Bibliographic Citation
- Korean Journal of Pharmacognosy, vol. 33, no. 2, pp. 137-143
- Publication Year
- 2002
- Abstract
- The inhibitory effects of methanol extracts of 165 medicinal herbs on matrix metalloproteinase-2 (MMP-2) activity were investigated. Amongst the herbal extracts, Youngia denticulate, Platycarya strobilacea, Sedum kamtschaticum, Euscaphis japonica, and Cornus controversa showed a significant inhibitory effect with above 80% at 1 μg/ml. Above mentioned five kind extracts, which exclude polyphenols and/or tannin by techniques for their removal, showed a mild inhibitory effect on MMP-2 activity except for Y. denticulate at the same concentration.
- Keyword
- matrix metalloproteinase-2youngia denticulate
- ISSN
- 0253-3073
- Publisher
- Korea Soc-Assoc-Inst
- Type
- Article
- Appears in Collections:
- Division of Bio Technology Innovation > SME Support Center > 1. Journal Articles
- Files in This Item:
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