Molecular phylogeny of endogenous retrovirus HERV-F family in japanese and rhesus monkeys

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dc.contributor.authorHeui Soo Kim-
dc.contributor.authorSeung Heui Jeon-
dc.contributor.authorJoo Mi Yi-
dc.contributor.authorTae Hyeong Kim-
dc.contributor.authorMyung Sook Kim-
dc.contributor.authorByung Hwa Hyun-
dc.contributor.authorOsamu Takenaka-
dc.date.accessioned2017-04-19T08:59:08Z-
dc.date.available2017-04-19T08:59:08Z-
dc.date.issued2002-
dc.identifier.issn1976-9571-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/5866-
dc.description.abstractA new human endogenous retroviral family (HERV-F) has recently been identified from the human chromosome 7q31.1-q31.3 that was identical to the XA34 cDNA clone isolated from a human glioma cDNA library with an ERV-9 probe. The current study investigated pol fragments of the HERV-F family from Japanese and rhesus monkeys and compared them with those of the HERV-F (Hu-XA34) family. Fourteen pol fragments of the HERV-F family were detected from the monkeys, which showed a 78.7 - 95.4% sequence similarity with those of HERV-F (Hu-XA34). Clones FJM-1, FJM-7, FJM-14, and FJM-15 from the Japanese monkey and FRH-1 and FRH-4 from the rhesus monkey exhibited no disruption due to point mutation or insertions/deletions. The ratio of synonymous to non-synonymous substitutions indicated that negative selective pressure was acting on these clones. Therefore, the pol gene sequences could be associated with an active provirus in the monkey genomes. A phylogenetic analysis of the pol fragments from humans and monkeys using the neighbor-joining and maximum parsimony methods showed six groups, indicating that either the HERV-F family was amplified at least six times after its original integration into the monkey genome or the occurrence of independent integration events during primate evolution.-
dc.publisherSpringer-
dc.titleMolecular phylogeny of endogenous retrovirus HERV-F family in japanese and rhesus monkeys-
dc.title.alternativeMolecular phylogeny of endogenous retrovirus HERV-F family in japanese and rhesus monkeys-
dc.typeArticle-
dc.citation.titleGenes & Genomics-
dc.citation.number2-
dc.citation.endPage139-
dc.citation.startPage133-
dc.citation.volume24-
dc.contributor.affiliatedAuthorByung Hwa Hyun-
dc.contributor.alternativeName김희수-
dc.contributor.alternativeName전승휴-
dc.contributor.alternativeName이주미-
dc.contributor.alternativeName김태형-
dc.contributor.alternativeName김명숙-
dc.contributor.alternativeName현병화-
dc.contributor.alternativeNameTakenaka-
dc.identifier.bibliographicCitationGenes & Genomics, vol. 24, no. 2, pp. 133-139-
dc.subject.keywordHERV-F family-
dc.subject.keywordHu-XA34-
dc.subject.keywordjapanese and rhesus monkeys-
dc.subject.keywordphylogeny-
dc.subject.keywordprimate evolution-
dc.subject.localHERV-F family-
dc.subject.localHu-XA34-
dc.subject.localjapanese and rhesus monkeys-
dc.subject.localphylogeny-
dc.subject.localPhylogeny-
dc.subject.localprimate evolution-
dc.description.journalClassY-
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