DC Field | Value | Language |
---|---|---|
dc.contributor.author | Heui Soo Kim | - |
dc.contributor.author | Seung Heui Jeon | - |
dc.contributor.author | Joo Mi Yi | - |
dc.contributor.author | Tae Hyeong Kim | - |
dc.contributor.author | Myung Sook Kim | - |
dc.contributor.author | Byung Hwa Hyun | - |
dc.contributor.author | Osamu Takenaka | - |
dc.date.accessioned | 2017-04-19T08:59:08Z | - |
dc.date.available | 2017-04-19T08:59:08Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 1976-9571 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/5866 | - |
dc.description.abstract | A new human endogenous retroviral family (HERV-F) has recently been identified from the human chromosome 7q31.1-q31.3 that was identical to the XA34 cDNA clone isolated from a human glioma cDNA library with an ERV-9 probe. The current study investigated pol fragments of the HERV-F family from Japanese and rhesus monkeys and compared them with those of the HERV-F (Hu-XA34) family. Fourteen pol fragments of the HERV-F family were detected from the monkeys, which showed a 78.7 - 95.4% sequence similarity with those of HERV-F (Hu-XA34). Clones FJM-1, FJM-7, FJM-14, and FJM-15 from the Japanese monkey and FRH-1 and FRH-4 from the rhesus monkey exhibited no disruption due to point mutation or insertions/deletions. The ratio of synonymous to non-synonymous substitutions indicated that negative selective pressure was acting on these clones. Therefore, the pol gene sequences could be associated with an active provirus in the monkey genomes. A phylogenetic analysis of the pol fragments from humans and monkeys using the neighbor-joining and maximum parsimony methods showed six groups, indicating that either the HERV-F family was amplified at least six times after its original integration into the monkey genome or the occurrence of independent integration events during primate evolution. | - |
dc.publisher | Springer | - |
dc.title | Molecular phylogeny of endogenous retrovirus HERV-F family in japanese and rhesus monkeys | - |
dc.title.alternative | Molecular phylogeny of endogenous retrovirus HERV-F family in japanese and rhesus monkeys | - |
dc.type | Article | - |
dc.citation.title | Genes & Genomics | - |
dc.citation.number | 2 | - |
dc.citation.endPage | 139 | - |
dc.citation.startPage | 133 | - |
dc.citation.volume | 24 | - |
dc.contributor.affiliatedAuthor | Byung Hwa Hyun | - |
dc.contributor.alternativeName | 김희수 | - |
dc.contributor.alternativeName | 전승휴 | - |
dc.contributor.alternativeName | 이주미 | - |
dc.contributor.alternativeName | 김태형 | - |
dc.contributor.alternativeName | 김명숙 | - |
dc.contributor.alternativeName | 현병화 | - |
dc.contributor.alternativeName | Takenaka | - |
dc.identifier.bibliographicCitation | Genes & Genomics, vol. 24, no. 2, pp. 133-139 | - |
dc.subject.keyword | HERV-F family | - |
dc.subject.keyword | Hu-XA34 | - |
dc.subject.keyword | japanese and rhesus monkeys | - |
dc.subject.keyword | phylogeny | - |
dc.subject.keyword | primate evolution | - |
dc.subject.local | HERV-F family | - |
dc.subject.local | Hu-XA34 | - |
dc.subject.local | japanese and rhesus monkeys | - |
dc.subject.local | phylogeny | - |
dc.subject.local | Phylogeny | - |
dc.subject.local | primate evolution | - |
dc.description.journalClass | Y | - |
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