Screening of inhibitory activity of medicinal plants against Heparinase = 수종 생약의 Heparinase 저해활성 검색

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Title
Screening of inhibitory activity of medicinal plants against Heparinase = 수종 생약의 Heparinase 저해활성 검색
Author(s)
Soon Cheol Ahn; Bo Yeon Kim; Won Keun Oh; Myung Sun Lee; Eun Young Bae; Dae Ook Kang; Jong Seog Ahn
Bibliographic Citation
Korean Journal of Pharmacognosy, vol. 33, no. 2, pp. 144-150
Publication Year
2002
Abstract
The methanol extracts of 132 herbal medicines were screened for the inhibitory activity against heparinase enzyme from Flavobacterium heparinum. Eleven medicinal plants, Amomum xanthiodides, Agrimonia pilosa, Paeonia lactiflora, Rubia cordifolia, Sanguisorba officinalis, Torrega grandis, Morus alba, Gleditsia sinensis, Crataegus pinnatifida, Cornus officinalis, Paeonia japonica showed potent inhibition on heparinase activity. The active substituents of those herbal medicine could be extracted into butanol fraction and the inhibitory compounds of Morus alba are now isolating.
Keyword
heparinase inhibitormedicinal plantsplant extractdrug activitydrug screeningmedicinal plant
ISSN
0253-3073
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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