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- Title
- Screening of inhibitory activity of medicinal plants against Heparinase = 수종 생약의 Heparinase 저해활성 검색
- Author(s)
- Soon Cheol Ahn; Bo Yeon Kim; Won Keun Oh; Myung Sun Lee; Eun Young Bae; Dae Ook Kang; Jong Seog Ahn
- Bibliographic Citation
- Korean Journal of Pharmacognosy, vol. 33, no. 2, pp. 144-150
- Publication Year
- 2002
- Abstract
- The methanol extracts of 132 herbal medicines were screened for the inhibitory activity against heparinase enzyme from Flavobacterium heparinum. Eleven medicinal plants, Amomum xanthiodides, Agrimonia pilosa, Paeonia lactiflora, Rubia cordifolia, Sanguisorba officinalis, Torrega grandis, Morus alba, Gleditsia sinensis, Crataegus pinnatifida, Cornus officinalis, Paeonia japonica showed potent inhibition on heparinase activity. The active substituents of those herbal medicine could be extracted into butanol fraction and the inhibitory compounds of Morus alba are now isolating.
- Keyword
- heparinase inhibitormedicinal plantsplant extractdrug activitydrug screeningmedicinal plant
- ISSN
- 0253-3073
- Publisher
- Korea Soc-Assoc-Inst
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
- Files in This Item:
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