New sesquiterpene-monoterpene lactone, artemisolide, isolated from Artemisia argyi

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Title
New sesquiterpene-monoterpene lactone, artemisolide, isolated from Artemisia argyi
Author(s)
Jong Han Kim; Hae Kyung Kim; Sun Bok Jeon; Kwang Hee Son; E H Kim; S K Kang; N D Sung; Byoung-Mog Kwon
Bibliographic Citation
Tetrahedron Letters, vol. 43, no. 35, pp. 6205-6208
Publication Year
2002
Abstract
A new sesquiterpene-monoterpene lactone, artemisolide, was isolated from the aerial parts of Artemisia argyi. The structure of artemisolide was elucidated by spectroscopic data including HMBC and NOESY. The structure was confirmed by X-ray crystallographic analysis. Artemisolide exhibited in vitro cytotoxic activity with GI50 values of 2-8 μM against cancer cell lines.
ISSN
0040-4039
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/S0040-4039(02)01315-1
Type
Article
Appears in Collections:
Division of Biomaterials Research > Industrial Bio-materials Research Center > 1. Journal Articles
Division of Biomedical Research > Genome Editing Research Center > 1. Journal Articles
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