Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2tm1Lau mice with dermatitis

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Title
Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2tm1Lau mice with dermatitis
Author(s)
Young Suk Won; H J Kwon; Goo Taeg Oh; Bang Hyun Kim; Chul Ho Lee; Y H Park; Byung Hwa Hyun; Yang Kyu Choi
Bibliographic Citation
Microbiology and Immunology, vol. 46, no. 9, pp. 629-632
Publication Year
2002
Abstract
Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knock-out mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice.
Keyword
Granulomatous dermatitisITS-PCRStaphylococcus xylosus
ISSN
0385-5600
Publisher
Wiley
DOI
http://dx.doi.org/10.1111/j.1348-0421.2002.tb02744.x
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Laboratory Animal Resource & Research Center > 1. Journal Articles
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