Production of useful secondary metabolites in plants : functional genomics approaches

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Title
Production of useful secondary metabolites in plants : functional genomics approaches
Author(s)
Jang Ryol Liu; D W Choi; H J Chung; S S Woo
Bibliographic Citation
Journal of Plant Biology, vol. 45, no. 1, pp. 1-6
Publication Year
2002
Abstract
The paradigm of biological research has been changed by recent developments in genomics, high-throughput biology, and bioinformatics. Conventional biology often was based on empirical, labor-intensive, and time-consuming methods. In the new paradigm, biological research e is driven by a holistic approach on the basis of rational, automatic, and high-throughput methods. New functional compounds can be discovered by using high-throughput screening systems. Secondary metabolite pathways and the genes involved in those pathways are then determined by studying functional genomics in conjunction with the data-mining tools of bioinformatics. In addition, these advances in metabolic engineering enable researchers to confer new secondary metabolic pathways to crops by transferring three to five, or more, heterologous genes taken from various other species. In the future, engineering for the production of useful compounds will be designed by a set of software tools that allows the user to specify a cell’s genes, proteins, and other molecules, as well as their individual interactions.
Keyword
bioinformaticshigh-throughput biologysecondary metabolism
ISSN
I000-0094
Publisher
Springer
DOI
http://dx.doi.org/10.1007/BF03030426
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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