Benzastatin J, a new demethylated derivative of benzastatin B produced by controlled fermentation of Streptomyces nitrosporeus

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Title
Benzastatin J, a new demethylated derivative of benzastatin B produced by controlled fermentation of Streptomyces nitrosporeus
Author(s)
Won Gon Kim; Ick Dong Yoo
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 12, no. 5, pp. 838-840
Publication Year
2002
Abstract
Feeding experiments of various derivatives of p-aminobenzamide to benzastatins-producing Streptomyces nitrosporeus were performed to observe whether new biosynthetic analogs of benzastatins were produced. The supplementation of p-aminobenzoic acid to the culture medium of Streptomyces nitrosporeus led to the production of benzastatin J, a new demethylated derivative of benzastatin B, while production of benzastatins A and B increased and benzastatins C-G were not detected.
Keyword
benzastatindemethylationp-aminobenzoic acidstreptomyces nitrosporeussupplementation
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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