Anti-human immunodeficiency virus-type 1 activity of constituents from Juglans mandshurica
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Byung Sun Min | - |
| dc.contributor.author | Hyeong Kyu Lee | - |
| dc.contributor.author | Sang Myung Lee | - |
| dc.contributor.author | Young Ho Kim | - |
| dc.contributor.author | K H Bae | - |
| dc.contributor.author | T Otake | - |
| dc.contributor.author | N Nakamura | - |
| dc.contributor.author | M Hattori | - |
| dc.date.accessioned | 2017-04-19T08:59:26Z | - |
| dc.date.available | 2017-04-19T08:59:26Z | - |
| dc.date.issued | 2002 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/5979 | - |
| dc.description.abstract | Three naphthalene glycosides (1-3), four flavonoids (4-7), and two galloyl glycosides (8-9) were isolated from the stem-bark of Juglans mandshurica (Juglandaceae). Their structures were determined by chemical and spectral means, including to 2D-NMR (COSY, HMQC, and HMBC) experiments. Amongst the isolated compounds, taxifolin (4) showed the most potent HIV-induced cytopethic activity against MT-4 cells with complete inhibitory concentration (IC100) value of 25 μg/ml and maximum cytotoxic concentration (CC100) value of above 100 μg/ml. However, naphthalene glycosides (1-3), flavonoids (5-7)), and galloyl tannins (8-9) were inactive against anti-HIV-1 activity. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | Anti-human immunodeficiency virus-type 1 activity of constituents from Juglans mandshurica | - |
| dc.title.alternative | Anti-human immunodeficiency virus-type 1 activity of constituents from Juglans mandshurica | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 4 | - |
| dc.citation.endPage | 445 | - |
| dc.citation.startPage | 441 | - |
| dc.citation.volume | 25 | - |
| dc.contributor.affiliatedAuthor | Byung Sun Min | - |
| dc.contributor.affiliatedAuthor | Hyeong Kyu Lee | - |
| dc.contributor.affiliatedAuthor | Sang Myung Lee | - |
| dc.contributor.affiliatedAuthor | Young Ho Kim | - |
| dc.contributor.alternativeName | 민병선 | - |
| dc.contributor.alternativeName | 이형규 | - |
| dc.contributor.alternativeName | 이상명 | - |
| dc.contributor.alternativeName | 김영호 | - |
| dc.contributor.alternativeName | 배기환 | - |
| dc.contributor.alternativeName | Otake | - |
| dc.contributor.alternativeName | Nakamura | - |
| dc.contributor.alternativeName | Hattori | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 25, no. 4, pp. 441-445 | - |
| dc.subject.keyword | anti-HIV activity | - |
| dc.subject.keyword | juglans mandshurica | - |
| dc.subject.keyword | MT-4 cells | - |
| dc.subject.keyword | taxifolin | - |
| dc.subject.local | anti-HIV activity | - |
| dc.subject.local | Juglans mandshurica | - |
| dc.subject.local | juglans mandshurica | - |
| dc.subject.local | MT-4 cells | - |
| dc.subject.local | Taxifolin | - |
| dc.subject.local | taxifolin | - |
| dc.description.journalClass | Y | - |
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