Antitumor activity of cultured mycelia of Ganoderma lucidum

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Title
Antitumor activity of cultured mycelia of Ganoderma lucidum
Author(s)
Byung Sun Min; Hyeong Kyu Lee; K H Bae; J J Gao; N Nakamura; M Hattori
Bibliographic Citation
Natural Products Sciences, vol. 8, no. 2, pp. 52-54
Publication Year
2002
Abstract
The cultured mycelia of fungus Ganoderma lucidum were investigated for the inhibitory effect on the growth of s.c. transplanted Lewis lung carcinoma (LLC) in BDF-1 mice by intraperitoneal (i.p.) administration. The cultured mycelia showed antitumor activity with T/C values of 89.6 and 50.3% at doses of 100 and 500 mg/kg, respectively, compared to adriamycin, which was used a positive control, with T/C value of 54.6% at 2 mg/kg.
Keyword
antitumor activitycultured myceliaganoderma lucidumlewis lung carcinomaganoderma lucidum extractantineoplastic activitydrug activity
ISSN
I000-0147
Publisher
Korean Society of Pharmacognosy
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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