Inhibitory effect of TNF-α and IL-8 secretion by pimarane-type diterpenoids from Acanthopanax koreanum
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | X F Cai | - |
| dc.contributor.author | G Shen | - |
| dc.contributor.author | N T Dat | - |
| dc.contributor.author | O H Kang | - |
| dc.contributor.author | J A Kim | - |
| dc.contributor.author | Y M Lee | - |
| dc.contributor.author | Jung Joon Lee | - |
| dc.contributor.author | Y H Kim | - |
| dc.date.accessioned | 2017-04-19T09:00:01Z | - |
| dc.date.available | 2017-04-19T09:00:01Z | - |
| dc.date.issued | 2003 | - |
| dc.identifier.issn | 0009-2363 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6162 | - |
| dc.description.abstract | A new pimarane-type diterpene compound, acanthokoreoic acid A together with three known compounds, acanthoic acid, acanthol, and sumogaside were isolated from a CH2Cl2 fraction of Acanthopanax koreanum by repeated column chromatography and reversed phase preparative HPLC. Acanthoic acid was isolated in high yields and showed potent inhibitory activity on the IL-8 secretion of the TNF-α-stimulated human colon adenocarcinoma cell line HT-29 and on the TNF-α secretion of the trypsin-stimulated human leukemic mast cell line HMC-1. | - |
| dc.publisher | Pharmaceutical Soc Japan | - |
| dc.title | Inhibitory effect of TNF-α and IL-8 secretion by pimarane-type diterpenoids from Acanthopanax koreanum | - |
| dc.title.alternative | Inhibitory effect of TNF-α and IL-8 secretion by pimarane-type diterpenoids from Acanthopanax koreanum | - |
| dc.type | Article | - |
| dc.citation.title | Chemical & Pharmaceutical Bulletin | - |
| dc.citation.number | 5 | - |
| dc.citation.endPage | 607 | - |
| dc.citation.startPage | 605 | - |
| dc.citation.volume | 51 | - |
| dc.contributor.affiliatedAuthor | Jung Joon Lee | - |
| dc.contributor.alternativeName | Cai | - |
| dc.contributor.alternativeName | Shen | - |
| dc.contributor.alternativeName | Dat | - |
| dc.contributor.alternativeName | 강옥화 | - |
| dc.contributor.alternativeName | 김진아 | - |
| dc.contributor.alternativeName | 이영미 | - |
| dc.contributor.alternativeName | 이정준 | - |
| dc.contributor.alternativeName | 김영호 | - |
| dc.identifier.bibliographicCitation | Chemical & Pharmaceutical Bulletin, vol. 51, no. 5, pp. 605-607 | - |
| dc.identifier.doi | 10.1248/cpb.51.605 | - |
| dc.subject.keyword | acanthopanax koreanum | - |
| dc.subject.keyword | diterpenoid | - |
| dc.subject.keyword | IL-8 | - |
| dc.subject.keyword | inhibitory effect | - |
| dc.subject.keyword | TNF-α | - |
| dc.subject.local | Acanthopanax koreanum | - |
| dc.subject.local | acanthopanax koreanum | - |
| dc.subject.local | Diterpenoid | - |
| dc.subject.local | Diterpenoids | - |
| dc.subject.local | diterpenoid | - |
| dc.subject.local | IL-8 | - |
| dc.subject.local | inhibitory effect | - |
| dc.subject.local | TNF-a | - |
| dc.subject.local | TNF-alpha | - |
| dc.subject.local | TNF-α | - |
| dc.subject.local | TNFa | - |
| dc.subject.local | TNFα | - |
| dc.subject.local | Tnf-α | - |
| dc.subject.local | Tumor necrosis fa tor-α | - |
| dc.subject.local | Tumor necrosis factor (TNF)-α | - |
| dc.subject.local | Tumor necrosis factor alpha | - |
| dc.subject.local | Tumor necrosis factor-alpha | - |
| dc.subject.local | Tumor necrosis factor-α | - |
| dc.subject.local | tumor necrosis factor-alpha | - |
| dc.subject.local | tumor necrosis factor-α | - |
| dc.description.journalClass | Y | - |
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