Lignans from Saururus chinensis inhibiting the transcription factor NF-κB

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dc.contributor.authorBang Yeon Hwang-
dc.contributor.authorJeong-Hyung Lee-
dc.contributor.authorJeong Bum Nam-
dc.contributor.authorYoung-Soo Hong-
dc.contributor.authorJung Joon Lee-
dc.date.accessioned2017-04-19T09:00:18Z-
dc.date.available2017-04-19T09:00:18Z-
dc.date.issued2003-
dc.identifier.issn0031-9422-
dc.identifier.uri10.1016/S0031-9422(03)00391-1ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6248-
dc.description.abstractThe sesquineolignans, saucerneol D and saucerneol E were isolated from the roots of Saururus chinensis together with four known lignans, manassantin A, manassantin B, (-)-saucerneol methyl ether, and (+)-saucernetin. Structure elucidation was based on the analysis of spectroscopic data and anti-inflammatory activity was studied using HeLa cells transfected with NF-κB reporter construct. All compounds except for (+)-saucernetin inhibited NF-κB dependent reporter gene expression with IC50 values of 2.5-16.9 μM.-
dc.publisherElsevier-
dc.titleLignans from Saururus chinensis inhibiting the transcription factor NF-κB-
dc.title.alternativeLignans from Saururus chinensis inhibiting the transcription factor NF-κB-
dc.typeArticle-
dc.citation.titlePhytochemistry-
dc.citation.number3-
dc.citation.endPage771-
dc.citation.startPage765-
dc.citation.volume64-
dc.contributor.affiliatedAuthorBang Yeon Hwang-
dc.contributor.affiliatedAuthorJeong-Hyung Lee-
dc.contributor.affiliatedAuthorJeong Bum Nam-
dc.contributor.affiliatedAuthorYoung-Soo Hong-
dc.contributor.affiliatedAuthorJung Joon Lee-
dc.contributor.alternativeName황방연-
dc.contributor.alternativeName이정형-
dc.contributor.alternativeName남정범-
dc.contributor.alternativeName홍영수-
dc.contributor.alternativeName이정준-
dc.identifier.bibliographicCitationPhytochemistry, vol. 64, no. 3, pp. 765-771-
dc.identifier.doi10.1016/S0031-9422(03)00391-1-
dc.subject.keywordlignan-
dc.subject.keywordnuclear factor κB-
dc.subject.keywordsaucerneol D-
dc.subject.keywordsaucerneol E-
dc.subject.keywordsaururaceae-
dc.subject.keywordsaururus chinensis-
dc.subject.keywordsesquineolignan-
dc.subject.locallignan-
dc.subject.localLignans-
dc.subject.localLignan-
dc.subject.locallignans-
dc.subject.localNuclear factor-kappa B-
dc.subject.localnuclear factor κB-
dc.subject.localNf-κb-
dc.subject.localNF-kB-
dc.subject.localnuclear factor kappa B-
dc.subject.localNF-κB (nuclear factor kappa-B)-
dc.subject.localNF-kappaB-
dc.subject.localNuclear factor-κb-
dc.subject.localNF-κ B-
dc.subject.localNF-κB-
dc.subject.localNF-kappa B-
dc.subject.localNuclear factor κB (NF-κB)-
dc.subject.localNuclear factor κB-
dc.subject.localNFκB-
dc.subject.localNf-κB-
dc.subject.localNuclear factor-κB-
dc.subject.localnuclear factorκB-
dc.subject.localNuclear factor (NF)-κB-
dc.subject.localNuclear factor kappa B-
dc.subject.localnuclear factor-κB-
dc.subject.localNF-ΚB-
dc.subject.localNuclear factor-kappa B (NF-κB)-
dc.subject.localNuclear factor-kappaB-
dc.subject.localnuclear factor-kappaB-
dc.subject.localnuclear factor-kappaB (NF-κB)-
dc.subject.localNFkappaB-
dc.subject.localNuclear factor kappaB-
dc.subject.localsaucerneol D-
dc.subject.localSaucerneol D-
dc.subject.localsaucerneol E-
dc.subject.localSaururaceae-
dc.subject.localsaururaceae-
dc.subject.localSaururus chinensis-
dc.subject.localsaururus chinensis-
dc.subject.localsesquineolignan-
dc.description.journalClassY-
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Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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