Stilbenes from the roots of Pleuropterus ciliinervis and their antioxidant activities

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Title
Stilbenes from the roots of Pleuropterus ciliinervis and their antioxidant activities
Author(s)
J P Lee; Byung Sun Min; Ren Bo An; M K Na; Sang Myung Lee; Hyeong Kyu Lee; J G Kim; K H Bae; S S Kang
Bibliographic Citation
Phytochemistry, vol. 64, no. 3, pp. 759-763
Publication Year
2003
Abstract
Two stilbene glycosides, pieceid-2″-O-gallate and pieceid-2″-O-coumarate, were isolated from the MeOH extract of the roots of Pleuropterus ciliinervis Nakai (Polygonaceae), together with two known compounds, resveratrol and pieceid. Their structures were determined spectroscopically, particularly by 2D NMR spectroscopic analysis. The antioxidant activities of stilbenes isolated were determined in vitro against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, superoxide radicals and by determining their lipid peroxidation inhibitory activities. Among the compounds isolated, pieceid-2″-O-gallate had the most potent inhibitory scavenging effect on DPPH, superoxide radicals and upon lipid peroxidation inhibition with IC50 values of 16.5, 23.9 and 5.1 μM, respectively.
Keyword
DPPH radical scavenging activitylipid peroxidation activitypieceid-2′-O-coumaratepieceid-2′-O-gallatepleuropterus ciliinervispolygonaceaesuperoxide radical scavenging activity
ISSN
0031-9422
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/S0031-9422(03)00417-5
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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