Dimerization of thyroglobulin in the endoplasmic reticulum = Thyroglobulin의 소포체내 dimerization

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dc.contributor.authorKee Sun Shin-
dc.contributor.authorO Y Kwon-
dc.date.accessioned2017-04-19T09:00:26Z-
dc.date.available2017-04-19T09:00:26Z-
dc.date.issued2003-
dc.identifier.issnI000-0052-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6285-
dc.description.abstractThe kinetics of dimerization of a newly synthesized thyroglobulin (Tg), the precursor protein in the manufacture of thyroid hormone, was investigated in the endoplasmic reticulum of thyrocytes FRTL-5 cell line. The folded monomeric Tg was first detectable in a conformationally unstable form, from the examination of lysates of pulse labeled cultured thyrocytes by denaturing and nondenaturing gel electrophoresis by 15 min after biosynthesis. The first dimeric Tg was formed by 30 min after; the monomer declined and the dimer progressively increased, and 40 min after remarkable dimeric Tg form was found. Finally, dimerization was complete at 60 min after.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleDimerization of thyroglobulin in the endoplasmic reticulum = Thyroglobulin의 소포체내 dimerization-
dc.title.alternativeDimerization of thyroglobulin in the endoplasmic reticulum-
dc.typeArticle-
dc.citation.titleKorean Journal of Life Sciences-
dc.citation.number3-
dc.citation.endPage251-
dc.citation.startPage248-
dc.citation.volume13-
dc.contributor.affiliatedAuthorKee Sun Shin-
dc.contributor.alternativeName신기선-
dc.contributor.alternativeName권오유-
dc.identifier.bibliographicCitationKorean Journal of Life Sciences, vol. 13, no. 3, pp. 248-251-
dc.subject.keywordthyroglobulin (Tg)-
dc.subject.keywordendoplasmic reticulum (ER)-
dc.subject.keywordtwo-dimensional electrophoresis (2-DE)-
dc.subject.localthyroglobulin-
dc.subject.localthyroglobulin (Tg)-
dc.subject.localEndoplasmic reticulum (ER)-
dc.subject.localendoplasmic reticulum (ER)-
dc.subject.localEndoplasmic reticulum-
dc.subject.localendoplasmic reticulum-
dc.subject.localtwo-dimensional electrophoresis-
dc.subject.localtwo-dimensional electrophoresis (2-DE)-
dc.description.journalClassN-
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Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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