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- Title
- The absolute configuration of prunioside A from Spiraea prunifolia and biological activities of related compounds
- Author(s)
- Hyun Cheol Oh; H S Shin; G S Oh; H O Pae; K Y Chai; H T Chung; H S Lee
- Bibliographic Citation
- Phytochemistry, vol. 64, no. 6, pp. 1113-1118
- Publication Year
- 2003
- Abstract
- The stereochemistry of prunioside A isolated from Spiraea prunifolia was determined by chemical transformations and NMR spectral data analysis, The configurations at C-5 and C-6 were determined to be 5S and 6R by application of the modified Mosher's method, CD analysis, and 13C NMR spectroscopic data analysis of an acetonide derivative. Other compounds related to prunioside A have inhibitory effects on the synthesis of nitric oxide in LPS-stimulated macrophage-like RAW 264.7 cells.
- Keyword
- inhibitory effects on nitric oxide (NO) productionmosher's methodprunioside Arosaceaespiraea prunifolia
- ISSN
- 0031-9422
- Publisher
- Elsevier
- DOI
- http://dx.doi.org/10.1016/S0031-9422(03)00499-0
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
- Files in This Item:
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