Synthesis of multi-substituted pyrazoles utilizing the N-alkylated 3-hydroxy-3-propargyl- or allenylisoindolines

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Title
Synthesis of multi-substituted pyrazoles utilizing the N-alkylated 3-hydroxy-3-propargyl- or allenylisoindolines
Author(s)
Y H Choi; Kyung Soon Kim; Sang Ku LeeTae Sook Jeong; H Y Lee; Y H Kim; Woo Song Lee
Bibliographic Citation
Heterocycles, vol. 60, no. 11, pp. 2499-2510
Publication Year
2003
Abstract
N-Alkyl-substituted phthalimides (1) were easily converted to di-, tri-, and tetra-substituted pyrazoles (10) via a one-pot addition-decyclization-cyclocondensation process. Then, the structure and the position of N1-substitution of the 1,3-pyrazole ring were determined by X-Ray crystallographic analysis and 1H-nOe experiments.
ISSN
0385-5414
Publisher
Elsevier
DOI
http://dx.doi.org/10.3987/COM-03-9869
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
Division of Biomaterials Research > Industrial Bio-materials Research Center > 1. Journal Articles
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
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