New polyacetylenes, DGAT inhibitors from the roots of Panax ginseng
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Seung Woong Lee | - |
| dc.contributor.author | K H Kim | - |
| dc.contributor.author | Mun Chual Rho | - |
| dc.contributor.author | Mi Yeon Chung | - |
| dc.contributor.author | Y H Kim | - |
| dc.contributor.author | Sangku Lee | - |
| dc.contributor.author | Hyun Sun Lee | - |
| dc.contributor.author | Young Kook Kim | - |
| dc.date.accessioned | 2017-04-19T09:00:58Z | - |
| dc.date.available | 2017-04-19T09:00:58Z | - |
| dc.date.issued | 2004 | - |
| dc.identifier.issn | 0032-0943 | - |
| dc.identifier.uri | 10.1055/s-2004-815534 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6454 | - |
| dc.description.abstract | The petroleum ether extract of Panax ginseng showed a significant inhibition of the diacylglycerol acyltransferase (DGAT) enzyme from rat liver microsomes. Bioactivity-guided fractionation led to the isolation of two new polyacetylenic compounds, (9R,10S)-epoxyheptadecan-4,6-diyn-3-one (1) and 1-methoxy-(9R,10S)-epoxyheptadecan-4,6-diyn-3-one (2). Their chemical structures were elucidated on the basis of spectroscopic evidence and asymmetric synthesis. IC50 values of 9 μg/mL (1) and 32 μg/ml (2) were obtained. | - |
| dc.publisher | Georg Thieme Verlag Kg | - |
| dc.title | New polyacetylenes, DGAT inhibitors from the roots of Panax ginseng | - |
| dc.title.alternative | New polyacetylenes, DGAT inhibitors from the roots of Panax ginseng | - |
| dc.type | Article | - |
| dc.citation.title | Planta Medica | - |
| dc.citation.number | 3 | - |
| dc.citation.endPage | 200 | - |
| dc.citation.startPage | 197 | - |
| dc.citation.volume | 70 | - |
| dc.contributor.affiliatedAuthor | Seung Woong Lee | - |
| dc.contributor.affiliatedAuthor | Mun Chual Rho | - |
| dc.contributor.affiliatedAuthor | Mi Yeon Chung | - |
| dc.contributor.affiliatedAuthor | Sangku Lee | - |
| dc.contributor.affiliatedAuthor | Hyun Sun Lee | - |
| dc.contributor.affiliatedAuthor | Young Kook Kim | - |
| dc.contributor.alternativeName | 이승웅 | - |
| dc.contributor.alternativeName | 김관회 | - |
| dc.contributor.alternativeName | 노문철 | - |
| dc.contributor.alternativeName | 정미연 | - |
| dc.contributor.alternativeName | 김영호 | - |
| dc.contributor.alternativeName | 이상구 | - |
| dc.contributor.alternativeName | 이현선 | - |
| dc.contributor.alternativeName | 김영국 | - |
| dc.identifier.bibliographicCitation | Planta Medica, vol. 70, no. 3, pp. 197-200 | - |
| dc.identifier.doi | 10.1055/s-2004-815534 | - |
| dc.subject.keyword | Araliaceae | - |
| dc.subject.keyword | Diacylglycerol acyltransferase (DGAT) | - |
| dc.subject.keyword | Panax ginseng | - |
| dc.subject.keyword | Polyacetylenes | - |
| dc.subject.keyword | Structure elucidation | - |
| dc.subject.local | Araliaceae | - |
| dc.subject.local | araliaceae | - |
| dc.subject.local | diacylglycerol acyltansferase (DGAT) | - |
| dc.subject.local | diacylglycerol acyltransferase | - |
| dc.subject.local | Diacylglycerol acyltransferase | - |
| dc.subject.local | Diacylglycerol acyltransferase (DGAT) | - |
| dc.subject.local | Panax ginseng | - |
| dc.subject.local | panax ginseng | - |
| dc.subject.local | Polyacetylene | - |
| dc.subject.local | Polyacetylenes | - |
| dc.subject.local | polyacetylene | - |
| dc.subject.local | Structure elucidation | - |
| dc.subject.local | structure elucidation | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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