Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Novel 3,5-diaryl pyrazolines as human acyl-CoA:cholesterol acyltransferase inhibitors
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- Title
- Novel 3,5-diaryl pyrazolines as human acyl-CoA:cholesterol acyltransferase inhibitors
- Author(s)
- Tae Sook Jeong; Kyung Soon Kim; So Jin An; Kyung Hyun Cho; Sangku Lee; Woo Song Lee
- Bibliographic Citation
- Bioorganic & Medicinal Chemistry Letters, vol. 14, no. 11, pp. 2715-2717
- Publication Year
- 2004
- Abstract
- A series of pyrazoline derivatives were prepared for evaluating their acyl-CoA:cholesterol acyltransferase activities. 3-(3,5-Di-tert-butyl-4- hydroxyphenyl)-5-(multi-substituted 4-hydroxyphenyl)-2-pyrazolines 4a-i were shown in vitro inhibitory activity on hACAT-1 and -2.
- Keyword
- ACAT inhibitor
- ISSN
- 0960-894X
- Publisher
- Elsevier
- Full Text Link
- http://dx.doi.org/10.1016/j.bmcl.2004.03.079
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
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