Synthesis of 4-Alkyl-1(2H)-phthalazinones and 4-Alkyl-2,3-benzoxazin-1-ones via ring Cleavage of 3-substituted N-Alkylated-3-hydroxyisoindolin-1-ones

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Title
Synthesis of 4-Alkyl-1(2H)-phthalazinones and 4-Alkyl-2,3-benzoxazin-1-ones via ring Cleavage of 3-substituted N-Alkylated-3-hydroxyisoindolin-1-ones
Author(s)
T G Chun; Kyung Soon Kim; Sangku LeeTae Sook Jeong; H Y Lee; Y H Kim; Woo Song Lee
Bibliographic Citation
Synthetic Communications, vol. 34, no. 7, pp. 1301-1308
Publication Year
2004
Abstract
N-Alkyl (Me, Et, i-Pr, t-Bu)-substituted phthalimdes 5a-d were easily transformed to 1(2H)-phthalazinones 8d-i and 2,3-benzoxazin-1-ones 9d, f, and j via a one-pot addition-decyclization-cyclocondensation process.
Keyword
heterocycleshydrazinen-alkylphthalimide
ISSN
0039-7911
Publisher
T&F (Taylor & Francis)
DOI
http://dx.doi.org/10.1081/SCC-120030319
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
Division of Biomaterials Research > Industrial Bio-materials Research Center > 1. Journal Articles
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
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