Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Inhibitory activity of diarylheptanoids on farnesyl protein transferase
Cited 23 time in 
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hyun Mi Kang | - |
| dc.contributor.author | Kwang Hee Son | - |
| dc.contributor.author | D C Yang | - |
| dc.contributor.author | Dong Cho Han | - |
| dc.contributor.author | Jong Han Kim | - |
| dc.contributor.author | N I Baek | - |
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.date.accessioned | 2017-04-19T09:01:04Z | - |
| dc.date.available | 2017-04-19T09:01:04Z | - |
| dc.date.issued | 2004 | - |
| dc.identifier.issn | 1029-2349 | - |
| dc.identifier.uri | 10.1080/14786410310001620691 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6492 | - |
| dc.description.abstract | Diarylheptanoids [curcumin (1), demethoxycurcumin (2), bisdemethoxycurcumin (3), bisdimethoxymethylcurcumin (4), and 1,2-dihydrobis(de-O-methyl)curcumin (5)] were isolated from the methanolic extract of Curcuma longa L. and a new cyclic diarylheptanoid (6) and a known Compound 7 were isolated from fruits of Alnus japonica Steud. Diarylheptanoids (1-3) inhibited farnesyl protein transferase (FPTase) with an IC50 of 29-50 μM. The other compounds very mildly inhibited FPTase, therefore, the inhibitory activity on FPTase very much depends on the structure of diarylheptanoids. | - |
| dc.publisher | T&F (Taylor & Francis) | - |
| dc.title | Inhibitory activity of diarylheptanoids on farnesyl protein transferase | - |
| dc.title.alternative | Inhibitory activity of diarylheptanoids on farnesyl protein transferase | - |
| dc.type | Article | - |
| dc.citation.title | Natural Product Research | - |
| dc.citation.number | 4 | - |
| dc.citation.endPage | 299 | - |
| dc.citation.startPage | 295 | - |
| dc.citation.volume | 18 | - |
| dc.contributor.affiliatedAuthor | Hyun Mi Kang | - |
| dc.contributor.affiliatedAuthor | Kwang Hee Son | - |
| dc.contributor.affiliatedAuthor | Dong Cho Han | - |
| dc.contributor.affiliatedAuthor | Jong Han Kim | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.alternativeName | 강현미 | - |
| dc.contributor.alternativeName | 손광희 | - |
| dc.contributor.alternativeName | 양덕조 | - |
| dc.contributor.alternativeName | 한동초 | - |
| dc.contributor.alternativeName | 김종한 | - |
| dc.contributor.alternativeName | 백남인 | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.identifier.bibliographicCitation | Natural Product Research, vol. 18, no. 4, pp. 295-299 | - |
| dc.identifier.doi | 10.1080/14786410310001620691 | - |
| dc.subject.keyword | Alnus japonica | - |
| dc.subject.keyword | Curcuma longa | - |
| dc.subject.keyword | Diarylheptanoids | - |
| dc.subject.keyword | Farnesyl protein transferase | - |
| dc.subject.local | Alnus japonica | - |
| dc.subject.local | Curcuma longa | - |
| dc.subject.local | diarylheptanoid | - |
| dc.subject.local | diarylheptanoids | - |
| dc.subject.local | Diarylheptanoid | - |
| dc.subject.local | Diarylheptanoids | - |
| dc.subject.local | Farnesyl protein transferase | - |
| dc.subject.local | Farnesyl-protein transferase (FPTase) | - |
| dc.subject.local | farnesyl protein transferase | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
Division of A.I. & Biomedical Research > Genomic Medicine Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.