Acyl-CoA: cholesterol acyltransferase inhibitory activities of fatty acid amides isolated from Mylabris phalerate Pallas
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ming-Zhe Xu | - |
| dc.contributor.author | Woo Song Lee | - |
| dc.contributor.author | Mi Jeong Kim | - |
| dc.contributor.author | Doo Sang Park | - |
| dc.contributor.author | Hana Yu | - |
| dc.contributor.author | G R Tian | - |
| dc.contributor.author | Tae Sook Jeong | - |
| dc.contributor.author | Ho Yong Park | - |
| dc.date.accessioned | 2017-04-19T09:01:17Z | - |
| dc.date.available | 2017-04-19T09:01:17Z | - |
| dc.date.issued | 2004 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | 10.1016/j.bmcl.2004.05.086 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6565 | - |
| dc.description.abstract | Unsaturated fatty acid amides, 9(Z)-octadecenamide (2) and 9(Z),12(Z)-octadecadienamide (4) as inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT) were isolated from the ethyl acetate extracts of the insect, Mylabris phalerate Pallas, and elucidated by their spectroscopic data analysis. Compounds 2 and 4 inhibited rat liver microsomal ACAT, hACAT-1, and hACAT-2 with IC50 values of 170, 85, and 63μM for 2 and of 151, 53, and 45μM for 4, respectively. | - |
| dc.publisher | Elsevier | - |
| dc.title | Acyl-CoA: cholesterol acyltransferase inhibitory activities of fatty acid amides isolated from Mylabris phalerate Pallas | - |
| dc.title.alternative | Acyl-CoA: cholesterol acyltransferase inhibitory activities of fatty acid amides isolated from Mylabris phalerate Pallas | - |
| dc.type | Article | - |
| dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
| dc.citation.number | 16 | - |
| dc.citation.endPage | 4280 | - |
| dc.citation.startPage | 4277 | - |
| dc.citation.volume | 14 | - |
| dc.contributor.affiliatedAuthor | Ming-Zhe Xu | - |
| dc.contributor.affiliatedAuthor | Woo Song Lee | - |
| dc.contributor.affiliatedAuthor | Mi Jeong Kim | - |
| dc.contributor.affiliatedAuthor | Doo Sang Park | - |
| dc.contributor.affiliatedAuthor | Hana Yu | - |
| dc.contributor.affiliatedAuthor | Tae Sook Jeong | - |
| dc.contributor.affiliatedAuthor | Ho Yong Park | - |
| dc.contributor.alternativeName | 서명철 | - |
| dc.contributor.alternativeName | 이우송 | - |
| dc.contributor.alternativeName | 김미정 | - |
| dc.contributor.alternativeName | 박두상 | - |
| dc.contributor.alternativeName | 유하나 | - |
| dc.contributor.alternativeName | Tian | - |
| dc.contributor.alternativeName | 정태숙 | - |
| dc.contributor.alternativeName | 박호용 | - |
| dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 14, no. 16, pp. 4277-4280 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2004.05.086 | - |
| dc.subject.keyword | ACAT inhibitors | - |
| dc.subject.keyword | Mylabris phalerate Pallas | - |
| dc.subject.keyword | The insect | - |
| dc.subject.local | ACAT inhibitor | - |
| dc.subject.local | ACAT inhibitors | - |
| dc.subject.local | Mylabris phalerate Pallas | - |
| dc.subject.local | The insect | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
Jeonbuk Branch Institute > 1. Journal Articles
Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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