A new VHR dual-specificity protein tyrosine phosphatase inhibitor from Dendrobium moniliforme
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Eun Young Bae | - |
| dc.contributor.author | Hyuncheol Oh | - |
| dc.contributor.author | Won Keun Oh | - |
| dc.contributor.author | Min Soo Kim | - |
| dc.contributor.author | Beom Seok Kim | - |
| dc.contributor.author | Bo Yeon Kim | - |
| dc.contributor.author | C B Sohn | - |
| dc.contributor.author | H Osada | - |
| dc.contributor.author | Jong Seog Ahn | - |
| dc.date.accessioned | 2017-04-19T09:01:26Z | - |
| dc.date.available | 2017-04-19T09:01:26Z | - |
| dc.date.issued | 2004 | - |
| dc.identifier.issn | 0032-0943 | - |
| dc.identifier.uri | 10.1055/s-2004-827238 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6618 | - |
| dc.description.abstract | Bioassay-guided fractionation of the EtOAc-soluble extract of Dendrobium moniliforme afforded a new phenanthraquinone-type metabolite, 7-hydroxy-5,6-dimethoxy-1,4-phenanthrenequinone (1), along with the previously reported 5-hydroxy-3,7-dimethoxy-1,4-phenanthrenequinone (2). The structures of the compounds were identified mainly on the basis of MS and NMR data. Compound 1 inhibited VHR dual-specificity protein tyrosine phosphatase (DS-PTPase) activity in a dose-dependent manner, displaying an IC50 value of 3.0 ± 0.2 μM. | - |
| dc.publisher | Georg Thieme Verlag Kg | - |
| dc.title | A new VHR dual-specificity protein tyrosine phosphatase inhibitor from Dendrobium moniliforme | - |
| dc.title.alternative | A new VHR dual-specificity protein tyrosine phosphatase inhibitor from Dendrobium moniliforme | - |
| dc.type | Article | - |
| dc.citation.title | Planta Medica | - |
| dc.citation.number | 9 | - |
| dc.citation.endPage | 870 | - |
| dc.citation.startPage | 869 | - |
| dc.citation.volume | 70 | - |
| dc.contributor.affiliatedAuthor | Eun Young Bae | - |
| dc.contributor.affiliatedAuthor | Hyuncheol Oh | - |
| dc.contributor.affiliatedAuthor | Won Keun Oh | - |
| dc.contributor.affiliatedAuthor | Min Soo Kim | - |
| dc.contributor.affiliatedAuthor | Beom Seok Kim | - |
| dc.contributor.affiliatedAuthor | Bo Yeon Kim | - |
| dc.contributor.affiliatedAuthor | Jong Seog Ahn | - |
| dc.contributor.alternativeName | 배은영 | - |
| dc.contributor.alternativeName | 오현철 | - |
| dc.contributor.alternativeName | 오원근 | - |
| dc.contributor.alternativeName | 김민수 | - |
| dc.contributor.alternativeName | 김범석 | - |
| dc.contributor.alternativeName | 김보연 | - |
| dc.contributor.alternativeName | 손천배 | - |
| dc.contributor.alternativeName | Osada | - |
| dc.contributor.alternativeName | 안종석 | - |
| dc.identifier.bibliographicCitation | Planta Medica, vol. 70, no. 9, pp. 869-870 | - |
| dc.identifier.doi | 10.1055/s-2004-827238 | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Jeonbuk Branch Institute > Microbial Biotechnology Research Center > 1. Journal Articles
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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