식용 식물자원으로부터 활성물질의 탐색-X.: 능소화(Campsis grandiflora K. schum.)로부터 지질화합물의 분리 및 FPTase 저해 효과 측정

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dc.contributor.authorD H Kim-
dc.contributor.authorM C Song-
dc.contributor.authorK M Han-
dc.contributor.authorM H Bang-
dc.contributor.authorByoung-Mog Kwon-
dc.contributor.authorS H Kim-
dc.contributor.authorD K Kim-
dc.contributor.authorI S Chung-
dc.contributor.authorM H Park-
dc.contributor.authorN I Baek-
dc.date.accessioned2017-04-19T09:01:40Z-
dc.date.available2017-04-19T09:01:40Z-
dc.date.issued2004-
dc.identifier.issnI0000171-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6664-
dc.description.abstractThe flower of Campsis grandiflora K. Schum. was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and H2O. From the EtOAc fraction, four compounds were isolated through the repeated silica gel and ODS column chromatographies. From the result of physico-chemical data including NMR, MS and IR, the chemical structures of the compounds were determined as linolenic acid methyl ester, linoleic acid methyl ester, β-sitosterol and daucosterol. Daucosterol inhibited FPTase activity with IC50 values of 14±0.04 μM.-
dc.publisherSpringer-
dc.title식용 식물자원으로부터 활성물질의 탐색-X.: 능소화(Campsis grandiflora K. schum.)로부터 지질화합물의 분리 및 FPTase 저해 효과 측정-
dc.title.alternativeDevelopment of biologically active compounds from edible plant sources-X.: isolation of lipids from the flower of Campsis grandiflora K. schum. and their inhibitory effect on FPTases-
dc.typeArticle-
dc.citation.titleJournal of Korean Society for Applied Biological Chemistry-
dc.citation.number3-
dc.citation.endPage360-
dc.citation.startPage357-
dc.citation.volume47-
dc.contributor.affiliatedAuthorByoung-Mog Kwon-
dc.contributor.alternativeName김동현-
dc.contributor.alternativeName송명종-
dc.contributor.alternativeName한경민-
dc.contributor.alternativeName방면호-
dc.contributor.alternativeName권병목-
dc.contributor.alternativeName김성훈-
dc.contributor.alternativeName김대근-
dc.contributor.alternativeName정인식-
dc.contributor.alternativeName박미현-
dc.contributor.alternativeName백남인-
dc.identifier.bibliographicCitationJournal of Korean Society for Applied Biological Chemistry, vol. 47, no. 3, pp. 357-360-
dc.subject.keywordcampsis grandiflora K. Schum.-
dc.subject.keywordlinoleic acid-
dc.subject.keywordlinolenic acid-
dc.subject.keywordβ-sitosterol-
dc.subject.keyworddaucosterol-
dc.subject.keywordFPTase-
dc.subject.localcampsis grandiflora K. Schum.-
dc.subject.locallinoleic acid-
dc.subject.localLinoleic acid-
dc.subject.locallinolenic acid-
dc.subject.localβ-sitosterol-
dc.subject.localdaucosterol-
dc.subject.localFPTase-
dc.description.journalClassY-
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Division of Biomedical Research > Genome Editing Research Center > 1. Journal Articles
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