Tetrahedron Letters, vol. 45, no. 48, pp. 8793-8795
Publication Year
2004
Abstract
An expedient synthesis of quinolactacin A2 from N-methylisatoic anhydride and N-Boc-(2S,3S)-isoleucine has been achieved. The key step involves the Friedl?nder-type annulation of isatoic anhydride and β-ketoester derived from isoleucine.