Identification of the Vibrio vulnificus cadC and evaluation of its role in acid tolerance

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dc.contributor.authorJ E Rhee-
dc.contributor.authorH M Ju-
dc.contributor.authorU Park-
dc.contributor.authorByoung Chul Park-
dc.contributor.authorS H Choi-
dc.date.accessioned2017-04-19T09:01:48Z-
dc.date.available2017-04-19T09:01:48Z-
dc.date.issued2004-
dc.identifier.issn1017-7825-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6706-
dc.description.abstractAn open reading frame encoding CadC, consisting of 526 amino acids, was identified from the upstream region of the Vibrio vulnificus cadBA operon. The deduced amino acid sequences of the cadC were 22 to 78% similar to those reported from other Enterobacteriaceae. Functions of cadC gene on acid tolerance were assessed by comparing acid tolerances of V. vulnificus and its isogenic mutant, whose cadC gene was inactivated by allelic exchanges. The results demonstrated that the gene product of cadC contributes to acid tolerance of V. vulnificus, and that its contribution is dependent on prior exposure of cells to moderately acidic pH. The cellular level of cadB and cadA transcripts decreased in the cadC mutant, indicating that CadC exerts its effect on acid tolerance of V. vulnificus by enhancing the expression of cadBA in a pH-dependent manner ?-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleIdentification of the Vibrio vulnificus cadC and evaluation of its role in acid tolerance-
dc.title.alternativeIdentification of the Vibrio vulnificus cadC and evaluation of its role in acid tolerance-
dc.typeArticle-
dc.citation.titleJournal of Microbiology and Biotechnology-
dc.citation.number5-
dc.citation.endPage1098-
dc.citation.startPage1093-
dc.citation.volume14-
dc.contributor.affiliatedAuthorByoung Chul Park-
dc.contributor.alternativeName이지은-
dc.contributor.alternativeName주현목-
dc.contributor.alternativeName박우령-
dc.contributor.alternativeName박병철-
dc.contributor.alternativeName최상호-
dc.identifier.bibliographicCitationJournal of Microbiology and Biotechnology, vol. 14, no. 5, pp. 1093-1098-
dc.subject.keywordacid tolerance-
dc.subject.keywordcadC-
dc.subject.keywordvibrio vulnificus-
dc.subject.localacid tolerance-
dc.subject.localAcid tolerance-
dc.subject.localCadC-
dc.subject.localcadC-
dc.subject.localvibrio vulnificus-
dc.subject.localVibrio vulnificus-
dc.description.journalClassY-
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Critical Diseases Diagnostics Convergence Research Center > 1. Journal Articles
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