DC Field | Value | Language |
---|---|---|
dc.contributor.author | M Na | - |
dc.contributor.author | K Bae | - |
dc.contributor.author | S S Kang | - |
dc.contributor.author | Byung Sun Min | - |
dc.contributor.author | J K Yoo | - |
dc.contributor.author | Y Kamiryo | - |
dc.contributor.author | Y Senoo | - |
dc.contributor.author | S Yokoo | - |
dc.contributor.author | N Miwa | - |
dc.date.accessioned | 2017-04-19T09:02:02Z | - |
dc.date.available | 2017-04-19T09:02:02Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0951-418X | - |
dc.identifier.uri | 10.1002/ptr.1529 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6760 | - |
dc.description.abstract | The ethanol extract from the fruit of Terminalia chebula (Combretaceae) exhibited significant inhibitory activity on oxidative stress and the age-dependent shortening of the telomeric DNA length. In the peroxidation model using t-BuOOH, the T. chebula extract showed a notable cytoprotective effect on the HEK-N/F cells with 60.5 ± 3.8% at a concentration of 50 μg/ml. In addition, the T. chebula extract exhibited a significant cytoprotective effect against UVB-induced oxidative damage. The life-span of the HEK-N/F cells was elongated by 40% as a result of the continuous administration of 3 μg/ml of the T. chebula extract compared to that of the control. These observations were attributed to the inhibitory effect of the T. chebula extract on the age-dependent shortening of the telomere, length as shown by the Southern blots of the terminal restriction fragments (TRFs) of DNA extracted from subculture passages. | - |
dc.publisher | Wiley | - |
dc.title | Cytoprotective effect on oxidative stress and inhibitory effect on cellular aging of Terminalia chebula fruit | - |
dc.title.alternative | Cytoprotective effect on oxidative stress and inhibitory effect on cellular aging of Terminalia chebula fruit | - |
dc.type | Article | - |
dc.citation.title | Phytotherapy Research | - |
dc.citation.number | 9 | - |
dc.citation.endPage | 741 | - |
dc.citation.startPage | 737 | - |
dc.citation.volume | 18 | - |
dc.contributor.affiliatedAuthor | Byung Sun Min | - |
dc.contributor.alternativeName | 나민균 | - |
dc.contributor.alternativeName | 배기환 | - |
dc.contributor.alternativeName | 강삼식 | - |
dc.contributor.alternativeName | 민병선 | - |
dc.contributor.alternativeName | 유재국 | - |
dc.contributor.alternativeName | Kamiryo | - |
dc.contributor.alternativeName | Senoo | - |
dc.contributor.alternativeName | Yokoo | - |
dc.contributor.alternativeName | Miwa | - |
dc.identifier.bibliographicCitation | Phytotherapy Research, vol. 18, no. 9, pp. 737-741 | - |
dc.identifier.doi | 10.1002/ptr.1529 | - |
dc.subject.keyword | Combretaceae | - |
dc.subject.keyword | Oxidative stress | - |
dc.subject.keyword | Southern blots | - |
dc.subject.keyword | Telomere length | - |
dc.subject.keyword | Terminalia chebula | - |
dc.subject.local | Combretaceae | - |
dc.subject.local | Oxidative stre | - |
dc.subject.local | Oxidative stress | - |
dc.subject.local | OXIDATIVE STRESS | - |
dc.subject.local | Oxidative Stress | - |
dc.subject.local | oxidative stress | - |
dc.subject.local | Southern blot | - |
dc.subject.local | southern blot | - |
dc.subject.local | Southern blots | - |
dc.subject.local | Telomere length | - |
dc.subject.local | Terminalia chebula | - |
dc.description.journalClass | Y | - |
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