Furo-1,2-naphthoquinones from Crataegus pinnatifida with ICAM-1 expression inhibition activity

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dc.contributor.authorByung Sun Min-
dc.contributor.authorH T T Huong-
dc.contributor.authorJung Hee Kim-
dc.contributor.authorH J Jun-
dc.contributor.authorM K Na-
dc.contributor.authorN H Nam-
dc.contributor.authorHyeong Kyu Lee-
dc.contributor.authorK Bae-
dc.contributor.authorS S Kang-
dc.date.accessioned2017-04-19T09:02:04Z-
dc.date.available2017-04-19T09:02:04Z-
dc.date.issued2004-
dc.identifier.issn0032-0943-
dc.identifier.uri10.1055/s-2004-835846ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6773-
dc.description.abstractTwo new furo-1,2-naphthoquinones, crataequinones A (1) and B (2), were isolated from the fruits of Crataegus pinnatifida. The structures of two new compounds were determined as 11,12-dimethoxy-3,4-furo-1,2-naphthoquinone (1) and 11,12-dimethoxy-5-hydroxy-3,4-furo-1,2-naphthoquinone (2) by spectroscopic analysis. The two compounds 1 and 2 showed significant inhibitory activity with IC50 values of 33 and 90 μM, respectively, against the expression of intercellular adhesion molecule-1 (ICAM-1).-
dc.publisherGeorg Thieme Verlag Kg-
dc.titleFuro-1,2-naphthoquinones from Crataegus pinnatifida with ICAM-1 expression inhibition activity-
dc.title.alternativeFuro-1,2-naphthoquinones from Crataegus pinnatifida with ICAM-1 expression inhibition activity-
dc.typeArticle-
dc.citation.titlePlanta Medica-
dc.citation.number12-
dc.citation.endPage1169-
dc.citation.startPage1166-
dc.citation.volume70-
dc.contributor.affiliatedAuthorByung Sun Min-
dc.contributor.affiliatedAuthorJung Hee Kim-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.alternativeName민병선-
dc.contributor.alternativeNameHuong-
dc.contributor.alternativeName김정희-
dc.contributor.alternativeName전현주-
dc.contributor.alternativeName나민균-
dc.contributor.alternativeNameNam-
dc.contributor.alternativeName이형규-
dc.contributor.alternativeName배기환-
dc.contributor.alternativeName강삼식-
dc.identifier.bibliographicCitationPlanta Medica, vol. 70, no. 12, pp. 1166-1169-
dc.identifier.doi10.1055/s-2004-835846-
dc.subject.keywordCrataegus pinnatifida-
dc.subject.keywordCrataequinone A-
dc.subject.keywordCrataequinone B-
dc.subject.keywordFuro-1,2-naphthoquinone-
dc.subject.keywordICAM-1 inhibitory activity-
dc.subject.keywordRosaceae-
dc.subject.localCrataegus pinnatifida-
dc.subject.localCrataequinone A-
dc.subject.localCrataequinone B-
dc.subject.localFuro-1,2-naphthoquinone-
dc.subject.localICAM-1 inhibitory activity-
dc.subject.localRosaceae-
dc.subject.localrosaceae-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
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