Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
Isoterreulactone A, a novel meroterpenoid with anti-acetylcholinesterase activity produced by Aspergillus terreus
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- Title
- Isoterreulactone A, a novel meroterpenoid with anti-acetylcholinesterase activity produced by Aspergillus terreus
- Author(s)
- Ick Dong Yoo; Kyung Mi Cho; C K Lee; Won Gon Kim
- Bibliographic Citation
- Bioorganic & Medicinal Chemistry Letters, vol. 15, no. 2, pp. 353-356
- Publication Year
- 2005
- Abstract
- A new seven-membered lactone type meroterpenoid, isoterreulactone A, was isolated from the solid state fermentation of Aspergillus terreus and its structure was established by various spectral analysis. Isoterreulactone A inhibited acetylcholinesterase with an IC50 value of 2.5 μM while did not inhibit butyrylcholinesterase even at 500 μM. A new seven-membered lactone type meroterpenoid, isoterreulactone A, was isolated from the solid state fermentation of Aspergillus terreus and its structure was established by various spectral analysis. Isoterreulactone A inhibited acetylcholinesterase with an IC50 value of 2.5 μM while did not inhibit butyrylcholinesterase even at 500 μM.
- ISSN
- 0960-894X
- Publisher
- Elsevier
- Full Text Link
- http://dx.doi.org/10.1016/j.bmcl.2004.10.067
- Type
- Article
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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